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Synergistic effects of melatonin and dienogest on pain relief in endometriosis: a randomized controlled trial.

Endometriosis affects 5-10% of reproductive-aged women and is characterized by chronic pelvic pain, dysmenorrhea, dyspareunia, and infertility. Standard hormonal therapies, such as dienogest, effectively manage symptoms, but are often associated …

Published: March 31, 2026, midnight
Reproductive Health Consequences of Per- and Polyfluoroalkyl Substances and Microplastics in Mid-life Women: A Systematic Review of Emerging Evidence.

Mid-life women are increasingly recognized as a vulnerable population for endocrine disruption due to chronic environmental exposures. Among emerging contaminants, per- and polyfluoroalkyl substances (PFAS) and microplastics have been implicated …

Published: March 31, 2026, midnight
Hypoxia-induced miR-21-5p promotes autophagy by downregulating CDC25A in endometriosis.

Endometriosis is a common gynecological disorder affecting women of reproductive age, often leading to chronic pain, reduced quality of life, and infertility. It is characterized by ectopic endometrial growth within …

Published: March 30, 2026, midnight
Differences in epigenetic age acceleration according to a diagnosis of endometriosis/adenomyosis: the Norwegian Mother, Father and Child Cohort Study.

Women with endometriosis and adenomyosis have an increased risk of age-dependent diseases such as cardiovascular disease and cancer. Whether this reflects differences in biological age is unknown.

Published: March 30, 2026, midnight
Demographic and hematological differences between endometriosis and menorrhagia in Saudi women: A retrospective observational study of 946 patients.

Endometriosis and menorrhagia are prevalent gynecological conditions with overlapping symptoms, yet comparative data from Middle Eastern populations remain scarce. We aimed to comprehensively characterize demographic and hematological differences between these …

Published: March 28, 2026, midnight
Probiotic supplementation improves quality of life and modulates oestradiol in women with endometriosis: a randomised double-blind pilot trial.

Endometriosis is a chronic, oestrogen-dependent inflammatory disorder affecting up to 10% of reproductive-age women, associated with pelvic pain, infertility, and reduced quality of life. Emerging evidence implicates the vaginal microbiome …

Published: March 27, 2026, midnight
Integrating Metabolic and MicroRNA Profiling to the Diagnostics of Endometriosis: A Pilot Study.

Endometriosis affects a large number of women of reproductive age, and its pathogenesis is still unclear. It causes severe chronic pelvic pain, which is often misdiagnosed as irritable bowel syndrome, …

Published: March 27, 2026, midnight
IVF in endometriosis: emerging evidence of exacerbation of pelvic pain and potential predictors.

Does IVF worsen pelvic pain in women with endometriosis?

Published: March 27, 2026, midnight
Contraceptive-Induced Weight Gain-Myth and Reality Review.

The perception that hormonal contraception causes weight gain is a general belief that frequently hinders the initiation and continuation of effective family planning. This narrative review analyses data from Cochrane …

Published: March 27, 2026, midnight
YWHAZ Loss Is Associated With Endometrial Dysfunction in Proliferative Phase Endometriosis.

Endometriosis is an estrogen-dependent inflammatory disorder frequently associated with infertility and characterized by progesterone resistance and impaired endometrial receptivity. While ectopic lesions define the disease, accumulating evidence indicates that molecular …

Published: March 26, 2026, midnight
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