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Downregulated METTL3 Accumulates TERT Expression that Promote the Progression of Ovarian Endometriosis.

Endometriosis is a complicated and enigmatic disease that significantly diminishes the quality of life for women affected by this condition. Increased levels of human telomerase reverse transcriptase (TERT) mRNA and …

Published: Dec. 31, 2024, midnight
Surface Molecular Markers for the Isolation of Viable Fibroblast Subpopulations in the Female Reproductive Tract: A Comprehensive Review.

Advancements in single-cell analyzis technologies, particularly single-cell RNA sequencing (scRNA-seq) and Fluorescence-Activated Cell Sorting (FACS), have enabled the analyzis of cellular diversity by providing resolutions that were not available previously. …

Published: Dec. 30, 2024, midnight
Nutrition Interventions in the Treatment of Endometriosis: A Scoping Review.

Pain, poor quality of life (QOL) and gastrointestinal (GI) symptoms are commonly experienced by individuals with endometriosis. Although diet and nutrition supplements are frequently used to manage endometriosis-related symptoms, there …

Published: Dec. 20, 2024, midnight
Müllerian anomalies and endometriosis: associations and phenotypic variations.

Müllerian anomalies are congenital conditions characterized by the incomplete development of the female reproductive tract. Women affected by Müllerian anomalies often display additional malformations of the renal, skeletal, and cardiovascular …

Published: Dec. 19, 2024, midnight
The correlation between immune cells and endometriosis: a bidirectional two-sample mendelian randomization study.

Endometriosis (EM), a prevalent estrogen-dependent inflammatory disorder affecting women of reproductive age, is characterized by the presence of endometrial-like tissue outside the uterus, resulting in pelvic scarring, pain, and infertility. …

Published: Dec. 19, 2024, midnight
Diagnostic Potential of Cytokine Biomarkers in Endometriosis: Challenges and Insights.

Endometriosis is a common gynecological condition affecting approximately 10% of women of reproductive age, characterized by the abnormal presence of endometrial-like tissue outside the uterus. Although endometriosis was first described …

Published: Dec. 17, 2024, midnight
Anogenital distance on MRI does not correlate to surgical diagnosis of endometriosis in patients without prior abdominal surgery.

Anogenital distance (AGD) is regarded as a potential biomarker for endometriosis, and a measurement on MRI images has been found to be promising. This study aimed to evaluate the measurement …

Published: Dec. 16, 2024, midnight
Histone lactylation-mediated overexpression of RASD2 promotes endometriosis progression via upregulating the SUMOylation of CTPS1.

Background: Histone lactylation is crucial in a variety of physiopathological processes, however, the function and mechanism of histone lactylation in endometriosis remain poorly understood. Therefore, the objective of this investigation …

Published: Dec. 13, 2024, midnight
A bioinformatics analysis of gene expression in endometrial cancer, endometriosis and obesity.

Endometrial cancer (EC), endometriosis (ENDO), and obesity (OBY) are interconnected conditions in women that may share underlying genetic pathways. This study aimed to identify shared genetic pathways and differential gene …

Published: Dec. 9, 2024, midnight
Unveiling the fibrotic puzzle of endometriosis: An overlooked concern calling for prompt action.

Endometriosis is a benign, estrogen-dependent, persistent chronic inflammatory heterogeneous condition that features fibrotic adhesions caused by periodic bleeding. The characteristic ectopic lesions are marked by a widely spread dense fibrotic …

Published: Dec. 3, 2024, midnight
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