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The surgical, histopathological characteristics, and survival outcome of ovarian clear cell carcinoma: a retrospective case series sharing the experience of a tertiary cancer centre.

Ovarian clear cell carcinoma (OCCC) is a rare and distinct subtype of epithelial ovarian cancer (EOC). It is unique in several biological aspects. This study analyzes the clinicopathological features and …

Published: Sept. 11, 2024, midnight
Single-cell analysis identifies distinct macrophage phenotypes associated with prodisease and proresolving functions in the endometriotic niche.

Endometriosis negatively impacts the health-related quality of life of 190 million women worldwide. Novel advances in nonhormonal treatments for this debilitating condition are desperately needed. Macrophages play a vital role …

Published: Sept. 10, 2024, midnight
R-954, a bradykinin B1 receptor antagonist, as a potential therapy in a preclinical endometriosis model.

Endometriosis is a gynecological condition characterized by the growth of endometrium-like tissues outside of the uterine cavity. Currently available drugs are efficacious in treating endometriosis-related pain, however it's not a …

Published: Sept. 10, 2024, midnight
Pregnancy-related decidualization in post-cesarean section scar endometriosis: A case report.

Post-cesarean section decidualized endometriosis is a rare phenomenon where ectopic endometrial cells undergo changes, such as atypia, under the influence of high progesterone levels at the site of cesarean section. …

Published: Sept. 10, 2024, midnight
Randomized, controlled, proof-of-concept trial of gefapixant for endometriosis-related pain.

To evaluate the P2X3 receptor antagonist, gefapixant, for treating moderate-to-severe endometriosis-related pain.

Published: Sept. 9, 2024, midnight
A rare presentation of hematosalpinx with torsion in a thirteen year-old virgin: a case report.

A medical condition called hematosalpinx causes an accumulation of blood within the fallopian tube. It is usually seen in patients with ectopic pregnancy. Inflammatory disease of the pelvis, tubal cancer, …

Published: Sept. 9, 2024, midnight
Correlation of anogenital distance from childhood to age 9 years-a prospective population-based birth cohort-the Odense Child Cohort.

Does anogenital distance (AGD) - distance from the anus to the genitals - correlate from infancy (3 months) to the age of 9 years in boys and girls?

Published: Sept. 9, 2024, midnight
Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records.

Endometriosis is a complex and heterogeneous condition affecting 10% of reproductive-age women, and yet, it often goes undiagnosed for several years. Limited observed heritability (7%) of large genetic association studies …

Published: Sept. 9, 2024, midnight
The vicious cycle of chronic endometriosis and depression-an immunological and physiological perspective.

Endometriosis is a chronic, estrogen-dependent, proinflammatory disease that can cause various dysfunctions. The main clinical manifestations of endometriosis include chronic pelvic pain and impaired fertility. The disease is characterized by …

Published: Sept. 6, 2024, midnight
Connecting the dots: Exploring appendiceal endometriosis in women with diaphragmatic endometriosis.

This study aims to ascertain the prevalence of appendiceal endometriosis (AppE) in patients diagnosed with diaphragmatic endometriosis (DiaE), compare it with the prevalence in patients without DiaE, and delineate the …

Published: Sept. 5, 2024, midnight
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