Endometriosis is a chronic inflammatory condition affecting 2-10% of reproductive-aged women, most commonly presenting with pelvic pain and subfertility. While its impact on reproductive health is increasingly recognized, the vaginal …
Treatment for women with endometriosis is only partially or temporarily effective. Moreover, medical hormonal treatment is associated with debilitating side effects and interferes with fertility, while surgery has a relatively …
Endometriosis is a chronic inflammatory condition, causing severe pelvic pain, organ dysfunction, infertility, and mental health issues. Ovarian reserve, indicating the quantity and quality of a woman's oocytes, is negatively …
Endometriosis is a chronic inflammatory disease strongly associated with reduced oocyte quality and subfertility, yet the underlying cytoplasmic defects remain poorly understood.
Endometriosis-associated pelvic pain represents a prototypical failure of systemic therapy for a locally organized, neuroinflammatory disease. Persistent pain arises from the convergence of estrogen-driven lesion survival, chronic inflammation, fibrosis, and …
Estrogen stimulates corticotropin-releasing hormone (CRH) expression in endometrial tissue, and CRH signaling contributes to inflammation and pain, suggesting a mechanistic role in endometriosis pathophysiology. We previously identified elevated CRH receptor-1 …
Endometriosis is a chronic, estrogen-dependent inflammatory disorder that causes substantial pain and infertility. Observational studies have reported higher rates of multiple psychiatric disorders among individuals with endometriosis; however, confounding and …
Small bowel herniation through a Caesarean section wound is exceedingly rare and may present with erythema and induration clinically indistinguishable from superficial wound infection, risking dangerous diagnostic delay. A case …
Endometriosis (EMS) is a highly heterogeneous chronic gynecological disease characterized by pain, infertility, and relapse, with its etiology and pathogenesis not yet fully elucidated. Traditional theories, including "retrograde menstruation," "implantation …
Chronic visceral pain affects over 20% of adults globally but remains poorly understood, significantly impacting quality of life and healthcare costs. Limited understanding and diagnostic misconceptions hinder effective management, particularly …