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MicroRNA profiling reveals potential biomarkers for the early transformation of endometriosis towards endometriosis-correlated ovarian cancer.

Endometriosis (EMS) is a chronic, gynecological condition affecting 6-10 % of reproductive-age women. While these lesions are benign, ovarian EMS presents cancer-like features, and can progress to endometriosis-correlated ovarian cancer …

Published: March 25, 2025, midnight
Narrative review on expression of non-coding RNA in biofluids in conditions associated with couple infertility.

Couple infertility poses a health challenge, prompting research into its multifaceted aetiology. Non-coding RNA (ncRNA) expression has emerged as a candidate for elucidating couple infertility. This review explores the roles …

Published: March 24, 2025, midnight
Postmenopausal endometriosis.

A postmenopausal woman, in her 60s, married with no history of pregnancy, presented to our facility with an abdominal mass of 2 months duration that progressively increased in size. Physical …

Published: March 14, 2025, midnight
Extracellular vesicles in endometrial-related diseases: role, potential and challenges.

Endometrial dysfunction underlies many common gynecologic disorders, such as endometriosis, endometrial cancer, intrauterine adhesions, and endometritis, which affect many women around the world. Extracellular vesicles play an important role in …

Published: March 12, 2025, midnight
Incidental Abdominal Wall Mass Diagnosed As Endometriosis: A Rare Finding in an Increasingly Common Pathology.

Endometriosis is becoming a well-discussed topic in the medical field of women's health, but rare and uncommon pathologic cases such as abdominal wall endometriosis are often overlooked in a patient's …

Published: March 9, 2025, midnight
Stem cell theory: A new horizon for the treatment of endometriosis by targeting mesenchymal stem cell.

Endometriosis is a prevalent chronic gynecological disease that poses significant challenges for treatment due to its extensive lesions, diverse morphology, unknown etiology, and tendency for recurrence. In the early 21st …

Published: March 7, 2025, midnight
Establishment of a Novel In Vitro and In Vivo Model to Understand Molecular Carcinogenesis of Endometriosis-Related Ovarian Neoplasms.

The molecular mechanisms through which endometriosis-related ovarian neoplasms (ERONs) develop from benign endometrioma remain unclear. It is especially a long-standing mystery why ovarian endometrioma has the potential to develop into …

Published: Feb. 25, 2025, midnight
Primary Low-Grade Endometrial Stromal Sarcoma of the Ovary Arising From Endometriosis: A Case Report.

Low-grade endometrial stromal sarcoma (LGESS) is a rare mesenchymal tumor of female genital tract malignancies. While it primarily arises in the uterus, extrauterine cases, including those originating in the ovary, …

Published: Feb. 23, 2025, midnight
A Fibronectin (FN)-Silk 3D Cell Culture Model as a Screening Tool for Repurposed Antifibrotic Drug Candidates for Endometriosis.

This study advances sustainable pharmaceutical research for endometriosis by developing in vitro 3D cell culture models of endometriotic pathophysiology that allow antifibrotic drug candidates to be tested. Fibrosis is a …

Published: Feb. 19, 2025, midnight
The integral roles of the TGFβ signaling pathway in uterine function and disease.

The uterus is a complex organ that requires precise signaling networks to mediate functions necessary for homeostasis and reproductive processes. The transforming growth factor β (TGFβ) superfamily regulates integral signaling …

Published: Feb. 14, 2025, midnight
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