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Modelling Endometriosis Using In Vitro and In Vivo Systems.

Endometriosis is a chronic inflammatory condition characterised by the presence of endometrium-like tissue outside the uterus. Despite its high prevalence and recent advances in molecular science, many aspects of endometriosis …

Published: Jan. 11, 2025, midnight
VEGF Expression Predicts Poor Prognosis in EC - Physician's Weekly

VEGF Expression Predicts Poor Prognosis in EC Physician's Weekly

Published: Jan. 10, 2025, 11:48 p.m.
Validation of Tumor Budding as a Prognostic Factor in Ovarian Clear Cell Carcinoma Using an Independent Cohort.

Ovarian clear cell carcinoma (OCCC) is an endometriosis-related neoplasm, in which traditional histologic grading does not show prognostic significance. Tumor budding was associated with poorer outcomes in OCCC in previous …

Published: Jan. 10, 2025, midnight
Spatial transcriptomic analysis identifies epithelium-macrophage crosstalk in endometriotic lesions.

The mechanisms underlying the pathophysiology of endometriosis, characterized by the presence of endometrium-like tissue outside the uterus, remain poorly understood. This study aimed to identify cell type-specific gene expression changes …

Published: Jan. 10, 2025, midnight
Antioxidant therapy for infertile couples: a comprehensive review of the current status and consideration of future prospects.

Oxidative stress (OS) is established as a key factor in the etiology of both male and female infertility, arising from an imbalance between reactive oxygen species (ROS) production and the …

Published: Jan. 9, 2025, midnight
Medical therapy to treat obesity and optimize fertility in women of reproductive age: a narrative review.

Overweight and obesity-chronic illnesses in which an increase in body fat promotes adipose tissue dysfunction and abnormal fat mass resulting in adverse metabolic, biomechanical, and psychosocial health consequences-negatively impact female …

Published: Jan. 6, 2025, midnight
ALKBH5 promotes autophagy and progression by mediating m6A methylation of lncRNA UBOX5-AS1 in endometriosis.

Long noncoding RNA (lncRNA) and N6-methyladenosine (m6A) methylation modification have recently been suggested as potential functional modulators in ovarian endometriosis, however, the function and mechanism of m6A-modified lncRNA in ovarian …

Published: Jan. 6, 2025, midnight
Late Eating Tied to Poor Glucose Tolerance - Physician's Weekly

Late Eating Tied to Poor Glucose Tolerance Physician's Weekly

Published: Jan. 3, 2025, 6:34 a.m.
Vitamin D and Endometriosis: Is There a Mechanistic Link?

Endometriosis is a prevalent chronic gynaecological disorder, but its cause is still unclear, and both genetic and environmental factors may contribute disease aetiology. Prominent amongst the latter is vitamin D …

Published: Jan. 2, 2025, midnight
Downregulated METTL3 Accumulates TERT Expression that Promote the Progression of Ovarian Endometriosis.

Endometriosis is a complicated and enigmatic disease that significantly diminishes the quality of life for women affected by this condition. Increased levels of human telomerase reverse transcriptase (TERT) mRNA and …

Published: Dec. 31, 2024, midnight
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