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Chemokine CCL21 promotes the pathological progression of endometriosis by regulating inflammatory cytokine expression and activating the NF-κB signaling pathway.

Endometriosis, affecting approximately 10% of reproductive-aged women worldwide, is widely recognized as a chronic inflammatory disease. Inflammation-related genes (IRGs) play a crucial role in the occurrence and progression of various …

Published: June 29, 2026, midnight
The opioid system in endometriosis: implications for endometrial receptivity and reproductive outcomes.

Endometriosis, a chronic inflammatory disease affecting 10-15% of women of reproductive age, remains a leading cause of female subfertility. While current management strategies focus on surgical excision and hormonal suppression, …

Published: June 29, 2026, midnight
FIN56-induced ferroptosis suppresses the development of endometriosis by augmenting mitochondrial ROS and lipid peroxidation via the ACACA/ARID5A/NOX4 axis.

Endometriosis (EMs) is one of the most common gynecologic diseases, and the roles of ferroptosis in EMs have not been fully clarified. The induction of ferroptosis has been demonstrated to …

Published: June 29, 2026, midnight
Bladder endometriosis: a current overview of pathogenesis, diagnosis, and treatment approaches.

Endometriosis is a chronic inflammatory disease affecting approximately 10% of women of reproductive age. Urinary tract involvement is rare, occurring in approximately 1-2% of cases, with the bladder being the …

Published: June 27, 2026, midnight
Patient-derived organoids in gynaecological cancers: emerging tools for therapy and disease modelling.

Patient-derived organoids (PDOs) have emerged as physiologically relevant three-dimensional (3D) culture systems that closely mimic the molecular and histological features of the human endometrium and associated malignancies. Owing to their …

Published: June 27, 2026, midnight
Diaphragmatic endometriosis: a practical radiologic guide to diagnosis, mapping, and multidisciplinary surgical planning.

Diaphragmatic endometriosis (DiaE) is a frequently underdiagnosed manifestation of deep endometriosis (DE), typically occurring in patients with advanced pelvic disease. Accurate preoperative detection remains challenging, as standard laparoscopy may overlook …

Published: June 26, 2026, midnight
The hypoxia-epigenetics-ncRNA axis in endometriosis: from molecular cascades to self-sustaining pathogenic circuits.

Endometriosis is a debilitating chronic inflammatory disorder driven by extensive molecular reprogramming. Despite significant bench research into its pathogenesis, translating these molecular discoveries into clinical practices that improve patient outcomes …

Published: June 26, 2026, midnight
Indications and Efficacy of Progestogen-Monotherapy as Menopause Hormone Therapy: A Narrative Review.

Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen …

Published: June 25, 2026, midnight
Salivary miRNAs in the diagnosis of endometriosis An invited narrative scientific literature review, commissioned by European Board and College of Obstetrics and Gynaecology (EBCOG).

Endometriosis is a common gynaecological condition, the diagnosis of which has been made for many years through invasive procedures, such as laparoscopy. In recent years, non-invasive methods have been proposed, …

Published: June 25, 2026, midnight
Catamenial Pneumothorax as an Underrecognized Manifestation of Thoracic Endometriosis: A 25-Year Single-Center Experience.

Objectives: Catamenial pneumothorax (CP) is a rare but clinically relevant cause of spontaneous pneumothorax (SP) in women and is associated with high recurrence rates. We hypothesized that CP is underrecognized …

Published: June 25, 2026, midnight
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