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EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apoptotic form of …

Published: Dec. 19, 2025, midnight
Coexistence of endometriosis and inflammatory bowel disease: a case series and practical diagnostic review.

The objective of this review is to identify key clinical lessons and highlight diagnostic and therapeutic strategies derived from case reports and recent literature. Particular attention is given to recognising …

Published: Dec. 18, 2025, midnight
Endometriosis Surgery: Debates About Restorative Reproductive Medicine.

For many patients with endometriosis, laparoscopic surgery is the most effective treatment to alleviate severe chronic pelvic pain and improve quality of life. Because endometriosis is common among individuals with …

Published: Dec. 18, 2025, midnight
Endometriosis Involving the Bladder: A Contemporary Clinicopathologic Analysis of 88 Patients.

Predominantly, case reports and small case series of endometriosis involving the bladder have been published. This study aimed to provide a contemporary clinicopathologic analysis of a large cohort of patients …

Published: Dec. 17, 2025, midnight
Natural conception and successful delivery after laparoscopic uterine anastomosis for traumatic cervical separation: a case report.

Traumatic separation of the cervix from the body of the uterus is exceedingly rare, particularly as a complication of pelvic fractures. This condition often poses significant diagnostic and therapeutic challenges, …

Published: Dec. 17, 2025, midnight
Thoracic Endometriosis Syndrome: A Systematic Review And Meta-analysis of Surgical Outcomes Among 1,182 patients over 25 years.

Without standardized guidelines, the management of thoracic endometriosis syndrome (TES) continues to fuel debate. Previous reviews have reported poor outcomes but lack data on complications, hospital length of stay (LOS) …

Published: Dec. 17, 2025, midnight
Borderline ovarian clear cell tumor arising from endometriosis during long-term dienogest therapy: a case report.

Endometriomas, commonly known as ovarian chocolate cysts, are a prevalent condition in women of reproductive age. They are cysts formed by the ectopic growth of endometrial tissue within the ovary, …

Published: Dec. 17, 2025, midnight
Caesarean scar endometriosis involving the uterine wall.

Endometriosis in a surgical scar is a rare but important clinical phenomenon that can lead to significant morbidity, especially in women with a history of caesarean sections. We present a …

Published: Dec. 16, 2025, midnight
Case Report: Two clinical cases of severe deep infiltrating endometriosis with infertility-transplantation first or surgery first? Natural cycle or artificial cycle?

Deep infiltrating endometriosis (DIE) is a severe condition frequently linked to infertility, yet the optimal integration of surgery and assisted reproductive technology (ART) remains controversial. This study reports two cases …

Published: Dec. 16, 2025, midnight
Compound design of a patient-derived 3D cell culture system modelling early peritoneal endometriosis.

Peritoneal endometriosis causes pelvic pain and infertility, but the underlying mechanisms related to these symptoms are not fully understood. Endometriosis diagnosis is typically delayed; thus, patient samples are unsuitable to …

Published: Dec. 15, 2025, midnight
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