Adenomyosis Pathophysiology, Diagnostic Advances, and Therapeutic Options.
Adenomyosis is a heterogeneous, nonmalignant uterine disorder characterized by ectopic endometrium within the myometrium, leading to abnormal uterine bleeding, dysmenorrhea, chronic pelvic pain, and subfertility. Once considered a disease of …
Diagnostic test accuracy of each of the four IDEA ultrasound steps in predicting presence of deep endometriosis.
To determine the diagnostic performance of each additional step of the four-step International Deep Endometriosis Analysis (IDEA) consensus protocol for predicting the presence of deep endometriosis (DE) on transvaginal ultrasound.
Stereoselectivity and functional plasticity of a common ligand-binding pocket in TRPM3.
The transient receptor potential melastatin 3 (TRPM3) channel is a key mediator of peripheral pain signaling, and pathogenic mutations in TRPM3 are linked to neurodevelopmental delay and epilepsy. Despite the …