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Multi-ancestry genome-wide association study of endometriosis and its clinical manifestations in ~1.4 million women: translating gene discovery into pathogenic mechanisms and therapeutic targets.

We conducted a multi-ancestry genome-wide association study of endometriosis and adenomyosis in almost 1.4 million women, including 105,869 cases, aiming to expand endometriosis loci discovery across ancestries, dissect symptom-specific effects, …

Published: Sept. 5, 2025, midnight
From First Breathless Episode to Final Diagnosis and Treatment: A Case Report on Thoracic Endometriosis Syndrome.

Background: Endometriosis is a chronic disease defined by the presence of endometrial-like tissue outside the uterine cavity. While typically confined to the pelvis, extrapelvic manifestations-including thoracic endometriosis-can occur. Although rare, …

Published: Sept. 4, 2025, midnight
Can bladder endometriosis be hard to diagnose? A two-case report and literature review.

Bladder endometriosis (BE) is an uncommon form of deep infiltrating endometriosis (DIE). This report aims to present two cases of BE with markedly contrasting clinical histories and presentations to highlight …

Published: Sept. 4, 2025, midnight
A Survey of the Reproductive Lesions in Captive Female Non-Human Primates in Italy.

Non-human primates (NHPs) are considered important models for the study of reproductive diseases, due to their anatomical and physiological similarities to humans. However, studies on spontaneous lesions of the reproductive …

Published: Sept. 4, 2025, midnight
Improving the reporting on health equity in observational research (STROBE-Equity): extension checklist and elaboration.

Published: Sept. 3, 2025, midnight
Triptorelin associated adverse events evaluated using FAERS pharmacovigilance data.

Triptorelin, a gonadotropin-releasing hormone(GnRH) agonist, is approved by the US Food and Drug Administration(FDA) for treating advanced prostate cancer, endometriosis, and central precocious puberty(CPP) in children aged ≥ 2 years. …

Published: Sept. 1, 2025, midnight
Adenomyosis-associated uterine rupture and pulmonary endometriosis mimicking advanced-stage uterine malignancy in an adolescent female: A case report.

Uterine adenomyosis and pulmonary endometriosis are exceptionally rare in adolescents and can pose significant diagnostic challenges due to their nonspecific clinical presentation and imaging features, which may mimic malignancy. Here, …

Published: Aug. 30, 2025, midnight
Perceived barriers and physical activity levels in women with endometriosis: The role of symptoms.

Endometriosis affects approximately 10 percent of women of reproductive age. Although physical activity has shown beneficial effects for managing endometriosis-related symptoms, women with this condition often engage in lower levels …

Published: Aug. 29, 2025, midnight
Reliability of self-reported endometriosis and adenomyosis data in online surveys: results from the ComPaRe-Endometriosis e-cohort.

How reliable are self-reported endometriosis or adenomyosis data compared with medical reports in online patient surveys?

Published: Aug. 29, 2025, midnight
Shaofu Zhuyu Decoction for Treating Endometriosis: A Systematic Review and Meta-Analysis.

Introduction: Shaofu Zhuyu Decoction (SZD) is a traditional Chinese herbal formula commonly used for gynecological disorders involving "blood stasis" and lower abdominal pain. Although applied clinically for endometriosis, evidence regarding …

Published: Aug. 29, 2025, midnight
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