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Risk of placenta previa in assisted reproductive technology: A Nordic population study with sibling analyses.

A higher risk of placenta previa after assisted reproductive technology (ART) is well established. The underlying mechanisms are poorly understood, but may relate to embryo culture duration, cryopreservation, and cause …

Published: Feb. 3, 2025, midnight
Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning.

Endometriosis (EMs) is a chronic inflammatory disease characterized by the presence of endometrial tissue in the non-uterine cavity, resulting in dysmenorrhea, pelvic pain, and infertility. Epidemiologic data have suggested the …

Published: Feb. 3, 2025, midnight
Peritoneal Endometriosis Impairs Ovarian Reserve and Increases Atresia in a Rat Model.

Background/Objectives: Endometriosis has a marked impact on fertility, although the mechanisms behind this relationship remain poorly understood, particularly in cases without significant anatomical distortions or in the context of ovarian …

Published: Feb. 3, 2025, midnight
The effect of endometriosis on oocyte quality: mechanisms, diagnosis and treatment.

Endometriosis significantly impacts the physical and mental health of women of reproductive age. While some patients can achieve pregnancy through surgery or in vitro fertilization (IVF), many still struggle with …

Published: Feb. 1, 2025, midnight
The effect of chronic inflammation on female fertility.

Inflammation has key biological roles in the battle against pathogens, and additional key processes in development and tissue homeostasis. However, when inflammation becomes chronic it can become a serious medical …

Published: Feb. 1, 2025, midnight
Hua Yu Xiao Zheng decoction induces ectopic endometrial stromal cell senescence via inhibiting the PI3K/AKT signaling.

Our purpose is to explore the influence of Hua Yu Xiao Zheng (HYXZ) decoction on the senescence of ectopic endometrial stromal cells (ESCs) in endometriosis as well as its relevant …

Published: Jan. 30, 2025, midnight
Mitochondrial dynamics: molecular mechanism and implications in endometriosis.

Endometriosis affects about 10% of women of reproductive age, leading to a disabling gynecologic condition. Chronic pain, inflammation, and oxidative stress have been identified as the molecular pathways involved in …

Published: Jan. 28, 2025, midnight
The myometrial transcriptome changes in mares with endometrosis.

Mares with endometrosis exhibit histological changes not only in the endometrium but also in the myometrium that suggest possible functional impairment. The molecular background of these changes is not well …

Published: Jan. 25, 2025, midnight
Reproductive outcomes in infertile women with endometriosis undergoing ART.

Background Endometriosis-related infertility and its treatment with assisted reproductive technologies (ART) have been broadly researched. Yet, underlying mechanisms of infertility, particularly in the absence of tubal dysfunction, remain unclear. While …

Published: Jan. 25, 2025, midnight
Cyclooxygenase 2 overexpression suppresses Smad3 and augments ERK1/2 signaling activated by TGFβ1 in endometrial stromal cells: a novel insight into endometriosis pathogenesis.

To investigate the underlying mechanisms driving the opposing effects of transforming growth factor-beta 1 (TGFβ1) on the proliferation of control (CESCs) and ectopic (EESCs) endometrial stromal cells.

Published: Jan. 24, 2025, midnight
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