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Elective uterine preservation: a novel concept to tackle reproductive ageing. Fertility preservation beyond ovaries.

With a growing number of women in developed countries having children later in life, it is time to rethink women's reproductive health. This trend of 'delayed parenthood' reflects a complex …

Published: Nov. 10, 2024, midnight
Menstruation: An Important Indicator for Assessing Stroke Risk and Its Outcomes.

In recent years, stroke incidence in older adults has declined strikingly, but stroke in younger women has become more common. Abnormalities of menstruation, the shedding of the uterine lining at …

Published: Nov. 7, 2024, midnight
Infertility, IL-17, IL-33 and Microbiome Cross-Talk: The Extended ARIA-MeDALL Hypothesis.

Infertility, defined as the inability to obtain pregnancy after 12 months of regular unprotected sexual intercourse, has increased in prevalence over the past decades, similarly to chronic, allergic, autoimmune, or …

Published: Nov. 7, 2024, midnight
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice.

Endometriosis is a debilitating and painful gynecological inflammatory disease affecting up to 15% of women and transgender men. Current treatments are ineffective for a substantial proportion of patients, underscoring the …

Published: Nov. 6, 2024, midnight
Is Osteopontin a Reliable Biomarker for Endometriosis?

This study aimed to evaluate the concentration of osteopontin in peritoneal fluid and plasma as potential biomarkers for diagnosing endometriosis. Osteopontin levels were measured using surface plasmon resonance imaging (SPRI) …

Published: Nov. 5, 2024, midnight
ACR Appropriateness Criteria® Endometriosis.

Endometriosis is a common condition impacting individuals assigned female at birth. Though incompletely understood, the disorder is caused by endometrial-like tissue located outside of the endometrial cavity, associated with inflammation …

Published: Nov. 4, 2024, midnight
Inflammatory Bowel Disease and Endometriosis: Diagnosis and Clinical Characteristics.

Background/Objectives: Endometriosis and inflammatory bowel disease (IBD) share some epidemiological, clinical and pathogenetic features. A differential diagnosis between pelvic endometriosis and IBD may be challenging, even for expert clinicians. In …

Published: Nov. 4, 2024, midnight
Extracellular Hsp70 and Circulating Endometriotic Cells as Novel Biomarkers for Endometriosis.

Stress-inducible heat shock protein 70 (Hsp70), which functions as a molecular chaperone and is frequently overexpressed in different cancer cell types, is present on the cell surface of tumor cells …

Published: Oct. 30, 2024, midnight
The causal role of gastroesophageal reflux disease in endometriosis: a bidirectional Mendelian randomization study.

Observational studies have reported an association between gastroesophageal reflux disease (GERD) and endometriosis. We conducted a two-sample and bidirectional Mendelian randomization analysis to determine whether those associations are causal. Two-sample …

Published: Oct. 30, 2024, midnight
Robot-assisted nerve-sparing eradication of deep endometriosis using the da Vinci SP.

The evolution of nerve-sparing surgery has been supported by a growing body of literature on anatomic details, dissection techniques, and functional outcomes, suggesting that nerve-sparing surgery for deep endometriosis (DE) …

Published: Oct. 25, 2024, midnight
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