Mechanisms of reproductive toxicity and endocrine disruption of bisphenols and per- and polyfluoroalkyl substances (PFAS): Implications for women's reproductive health.
Bisphenols and per- and polyfluoroalkyl substances (PFAS) are ubiquitous environmental endocrine-disrupting chemicals with widespread human exposure and growing concern regarding their reproductive toxicity. This review integrates current experimental and epidemiologic …
Prevalence, predictors, and clinical relevance of drug-drug interactions in outpatient prescribing: A national cross-sectional study.
Drug-drug interactions (DDIs) represent a major preventable cause of medication-related harm globally. Their prevalence varies across health systems, but common drivers include polypharmacy, aging populations, and specialty-specific prescribing patterns. Large-scale …
Unusual presentation of endometriosis as a large tubo-ovarian abscess posing a diagnostic challenge.
Tubo-ovarian abscess (TOA) is a severe complication of pelvic inflammatory disease (PID), but it can also occur in women without prior PID or sexually transmitted infections. Recent studies suggest that …
Prenatal bisphenol A exposure reprograms SF1-lactylation pathways to promote endometriosis susceptibility.
Endometriosis is an estrogen-dependent disorder influenced by dysregulated steroidogenesis, oxidative stress, and inflammation. Bisphenol A (BPA), a common endocrine disruptor, has been associated with reproductive dysfunction, but its developmental impacts …