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Macrophage membrane-biomimetic nanovehicles delivering amygdalin halt pyroptosis propagation and alleviate endometriosis-associated neuropathic pain.

The clinical management of endometriosis encounters a significant obstacle: existing therapies inadequately address both the inhibition of ectopic lesion proliferation and the mitigation of the neuroinflammation associated with chronic pain. …

Published: April 20, 2026, midnight
Analyzing the Risk Factors for Recurrence of Endometrioma and Dysmenorrhea in Patients with Endometriosis.

Recurrence of endometrioma and dysmenorrhea after surgery remains a major clinical challenge. Identifying reliable risk factors is essential to optimize individualized treatment and follow-up strategies. However, large-scale data from Chinese …

Published: April 19, 2026, midnight
Exploring the mechanisms of luteolin in treating polycystic ovary syndrome and endometriosis via network pharmacology, molecular docking, and molecular dynamics simulation.

This study aims to elucidate the molecular mechanisms underlying luteolin's therapeutic effects on polycystic ovary syndrome (PCOS) and endometriosis (EM), thereby providing a theoretical foundation for developing novel treatment strategies. …

Published: April 18, 2026, midnight
Histological and immunohistochemical characteristics of superficial peritoneal endometriotic lesions of clinical responders and non-responders to dienogest treatment.

Are there histological and immunohistochemical patterns of superficial peritoneal endometriotic lesions of symptomatic patients that characterize non-response to dienogest treatment and may suggest progesterone resistance?

Published: April 18, 2026, midnight
Polypoid endometriosis mimicking aggressive pelvic malignancy on MRI in a premenopausal woman: A case report.

Polypoid endometriosis is a rare benign variant of endometriosis characterized by exuberant mass-forming endometrial tissue that can closely mimic aggressive pelvic malignancy on imaging. Although it most commonly affects peri- …

Published: April 18, 2026, midnight
Analgesic and Anti-Inflammatory Activity of Ambroxol in the Treatment of Endometriosis: An Experimental Study in Wistar Rats.

Background/Objective: This study evaluated the analgesic and anti-inflammatory effects of ambroxol in an experimental model of endometriosis. Methods: Ambroxol was administered at doses of 10, 50, and 100 mg/kg (Abx …

Published: April 18, 2026, midnight
ACOG updates guidance for evaluating postmenopausal bleeding - Contemporary OB/GYN

ACOG updates guidance for evaluating postmenopausal bleeding Contemporary OB/GYN

Published: April 17, 2026, 7:46 p.m.
Curcumin modulates the function of SPP1+ macrophages via NF-κB signaling to alleviate endometriosis.

Endometriosis is a complex gynecological disorder with prominent cellular heterogeneity, and its key pathogenic cell subsets and core molecular mechanisms remain elusive, which restricts the development of effective therapeutic strategies. …

Published: April 17, 2026, midnight
Transdisciplinary Approach to Endometriosis-Related Chronic Pelvic Pain in Colombia: A Consensus Statement for Patient-Centered Care.

This consensus statement seeks to transform endometriosis care in Colombia by standardizing clinical management through the establishment of transdisciplinary teams and the use of quality indicators; strengthening education and awareness …

Published: April 17, 2026, midnight
Inflammasomes meet organoids and artificial intelligence: unraveling the complexity of gynecological inflammation.

Gynecological diseases represent a persistent global health burden. According to a WHO report, the global incidence of gynecological diseases exceeds 65%. Furthermore, over 90% of women suffer from gynecological issues …

Published: April 17, 2026, midnight
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