Microbiota and infertility: a translational review of mechanisms and clinical applications in assisted reproduction.
Infertility constitutes a major global health concern, affecting approximately 17.5% of couples of reproductive age. Although advances in assisted reproductive technologies (ART) have expanded treatment options, success rates remain highly …
Botulinum toxin for endometriosis-associated chronic pelvic pain: a randomised, double-masked, parallel, phase 2 trial.
Chronic pelvic pain affects one in four women. Botulinum toxin, approved for chronic migraine and cervical dystonia pain, is an emerging treatment for other pain conditions. We evaluated intramuscular pelvic …
Endometriosis and Reproductive Sparing Surgery: A Narrative Review and AGREE II-S-Based Evaluation of International Guidelines.
Endometriosis is a complex disease that may affect a woman's fertility and quality of life. Owing to substantial variations in symptom severity, lesion distribution, and reproductive impact, its management presents …
Expression of concern: "Is dienogest a convenient treatment option for cesarean scar endometriosis or should it be treated surgically?". [Eur. J. Obstet. Gynecol. Reprod. Biol. 282 (2023) 110-115].
IL-8 and follicular fluid: insights into the mechanisms of endometriosis development.
Endometriosis is a common gynaecological condition characterised by the growth of endometrial-like tissue both within the muscular layer of the uterus and outside of it, affecting 10-15 % of women …
Regarding "Trends in endometriosis Management: a 10 year US Claims Analysis".
Surgery is chosen over pharmacological treatment, probably due to the limitations of medical therapy, pregnancy, the preferences of patients and physicians, and the psychological perception of a more definitive symptom …
Beyond VEGF and TGF-β: A Comprehensive Review of Growth Factor Pathways in the Pathophysiology of Uterine Leiomyomas.
Uterine leiomyomas or fibroids, are non-cancerous smooth muscle proliferations of the uterus, occurring mostly in women of reproductive age. Their pathogenesis involves complex growth factor interactions that regulate cellular proliferation, …