Single-cell RNA sequencing is a state-of-the-art approach to decipher the heterogeneity of RNA transcripts in individual cells and identify different cell types in tissues and organs. Its aim is to …
This study aimed to evaluate the impact of an 8 weeks functional strength training program on physical performance, pain perception, and quality of life in women with endometriosis.
Deep infiltrating endometriosis (DIE) is associated with substantial impairment in health-related quality of life (HRQoL), affecting pain, emotional well-being, sexual functioning, and daily activities. Previous studies have shown that laparoscopic …
Endometriosis is a chronic estrogen-dependent disorder characterised by the growth of endometrial-like tissues outside the uterus. Recent data suggest a potential role for endometrial stem/progenitor cells in the development of …
Endometriosis is a chronic, hormone-dependent disease characterized by altered endometrial stromal function, but mechanistic and translational studies have been hindered by the lack of tractable human models. Here, we establish …
Endometrial organoids are a powerful, 3D in vitro system for studying reproductive function and disease since they are more physiologically representative than 2D cell models. However, optimal methods for the …
Endometriosis, defined as the ectopic growth of endometrial tissue outside of the uterine cavity, is an inflammatory and hormone-dependent disease that causes excruciating pelvic pain, infertility, and significantly decreases quality …
Endometriosis affects approximately 10% of reproductive-age women and up to 20% of those with infertility. Despite rising awareness in adults, adolescent endometriosis remains underrecognized, especially in Southeast Asia. This study …
Endometriosis is frequently managed with hormonal suppression that can induce hypoestrogenism during a period when many patients are still accruing peak bone mass. This narrative review summarizes current clinical and …