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Targeting HSP90 as a therapeutic approach for endometriosis: insights from proteomic analysis.

Endometriosis, a chronic inflammatory condition characterized by pain and infertility, remains a clinical challenge. Current hormonal and surgical treatments are often limited by side effects and high recurrence rates. In …

Published: Feb. 7, 2026, midnight
Endometriosis-derived exosomal MicroRNA-125b-5p downregulates phosphatidylinositol 3-Kinase/Protein Kinase B signaling pathways via vascular endothelial growth factor to decelerate endometriosis progression.

Endometriosis (EMs) is a chronic enigmatic gynecological disorder which pathogenesis have not been fully elucidated. Exosomes have been proven to participate in endometriosis. However, the role of exosomes in the …

Published: Feb. 7, 2026, midnight
Primary peritoneal clear cell carcinoma with metastasis mimicking ovarian carcinoma: a case report and literature review.

Primary peritoneal clear cell carcinoma (PPCCC) is an exceptionally rare malignancy that closely resembles gynecologic epithelial cancers clinically and histologically. Its pathogenesis is poorly understood, with possible origins from Müllerian …

Published: Feb. 7, 2026, midnight
Diagnostic disparities in endometriosis and adenomyosis: investigating social vulnerability and access to care in an ancestrally diverse population.

To evaluate differences in the likelihood of endometriosis or adenomyosis diagnosis across genetically-defined ancestry groups (African, Admixed American, East Asian, European, and South Asian), and to determine whether social vulnerability …

Published: Feb. 7, 2026, midnight
Shorter Anogenital Distance in Women with Adenomyosis Diagnosed by MUSA 2022 Criteria: A Prospective Case-Control Study.

Objective: The objective was to investigate the association between anogenital distance (AGD) and adenomyosis in reproductive-age women and to evaluate the potential of AGD as a non-invasive biomarker reflecting prenatal …

Published: Feb. 7, 2026, midnight
Parthenolide attenuated the endometriosis-like lesions by activating autophagy and suppressing NLRP3 inflammasome activity.

Parthenolide (PTL) has significant anti-inflammatory and immunomodulatory effects, but its regulatory mechanisms in endometriosis (EMs) remain unclear. This study aimed to systematically evaluate the effects of PTL on cellular models …

Published: Feb. 6, 2026, midnight
Enhanced CD56 Expression and Increased Number of CD56+bright Cells in the Peripheral Blood of Untreated Endometriosis Patients.

NK-cell dysfunction in endometriosis is suggested to contribute to the survival of ectopic endometrial tissue. However, the underlying causes of this impairment remain unclear. NK cells are divided into: CD56+bright, …

Published: Feb. 6, 2026, midnight
Shared Decision Making among Patients with Chronic Conditions in France: A Cross-Sectional Survey in the ComPaRe E-Cohort.

BackgroundShared decision making (SDM) is a cornerstone of patient-centered care; however, little information is available on how SDM is practiced in routine care. We aimed to assess the level of …

Published: Feb. 6, 2026, midnight
Development and validation of a clinical nomogram for predicting cumulative live birth rate in ovarian endometrioma patients undergoing ethanol sclerotherapy and in vitro fertilization/intracytoplasmic sperm injection.

Effective individualized tools to predict cumulative live birth rates are lacking for patients with ovarian endometriomas undergoing In Vitro Fertilization or Intracytoplasmic Sperm Injection after ultrasound-guided ethanol sclerotherapy. This study …

Published: Feb. 6, 2026, midnight
Efficacy and Safety of Traditional Chinese Medicine Retention Enema for Endometriosis: A Systematic Review and Meta-Analysis.

Background/Objectives: Herbal retention enema is widely used in Traditional Chinese Medicine for the management of endometriosis; however, its clinical efficacy and safety have not been systematically evaluated. Methods: Ten electronic …

Published: Feb. 6, 2026, midnight
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