Bridging the Diagnostic Gap: Reviewing Current Endometriosis Screening Tools and Models.
Background: Endometriosis affects 10% of reproductive-aged women globally and is one of the major causes of infertility. It is a debilitating, chronic condition with an average diagnostic delay of up …
Hormonal therapies for endometriosis-associated pain: inflammatory limitations and pharmacological challenges.
Endometriosis is a chronic inflammatory and estrogen-dependent disease in which pain remains the leading cause of impaired quality of life. Hormonal therapies constitute the cornerstone of medical management and include …
Endometriosis and ovarian aging: a pilot study exploring oxidative stress and DNA damage markers.
To assess whether specific markers of oxidative stress and DNA damage are expressed at higher levels in primordial follicles of patients with endometriomas compared to age-matched controls.
Integrated lipidomics and transcriptomics reveal the key role of ceramides in the development of endometriosis.
Endometriosis (EMs) is a chronic gynecological disease with poorly understood pathogenesis. This study integrated lipidomics and transcriptomics to systematically investigate aberrant sphingolipid metabolism in EMs, aiming to identify pathogenic mechanisms …