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Impacts of Phyllanthus niruri extract on biomarker levels, macrophage count, and lesion area in an endometriotic rat model.

Endometriosis is a gynecological disorder characterized by chronic inflammation, anatomical changes, prolonged pain, and infertility. On the other hand, Phyllanthus niruri is recognized for its pharmacological effects, which might be …

Published: Sept. 10, 2024, midnight
Evidence of Browning and Inflammation Features in Visceral Adipose Tissue of Women with Endometriosis.

Patients with endometriosis tend to have a low body mass index, suggesting an inverse relationship between body fat and risk of disease. This is supported by evidence that miRNAs differentially …

Published: Sept. 7, 2024, midnight
The vicious cycle of chronic endometriosis and depression-an immunological and physiological perspective.

Endometriosis is a chronic, estrogen-dependent, proinflammatory disease that can cause various dysfunctions. The main clinical manifestations of endometriosis include chronic pelvic pain and impaired fertility. The disease is characterized by …

Published: Sept. 6, 2024, midnight
Endometriosis and aspirin: a systematic review.

Endometriosis is delineated as a benign yet steroid-dependent disorder characterized by the ectopic presence of endometrial glandular and stromal cells outside the uterine cavity, affecting estimated 10%-15% of women of …

Published: Aug. 27, 2024, midnight
Post traumatic stress disorder associated hypothalamic-pituitary-adrenal axis dysregulation and physical illness.

Conventional human stress responses are mediated by the sympathetic adrenal medullar (SAM) axis and the hypothalamic pituitary adrenal (HPA) axis. The SAM axis mediates the immediate response to stress through …

Published: Aug. 20, 2024, midnight
Vaginal and rectal microbiome contribute to genital inflammation in chronic pelvic pain - BMC Medicine

Vaginal and rectal microbiome contribute to genital inflammation in chronic pelvic pain BMC Medicine

Published: July 8, 2024, 7 a.m.
Melatonin: Current evidence on protective and therapeutic roles in gynecological diseases.

Melatonin, a potent antioxidant and free radical scavenger, has been demonstrated to be effective in gynecological conditions and female reproductive cancers. This review consolidates the accumulating evidence on melatonin's multifaceted …

Published: March 11, 2024, midnight
Luteolin attenuates Staphylococcus aureus -induced endometritis through inhibiting ferroptosis and inflammation via activating the Nrf2/GPX4 signaling pathway - American Society for Microbiology

Luteolin attenuates Staphylococcus aureus -induced endometritis through inhibiting ferroptosis and inflammation via activating the Nrf2/GPX4 signaling pathway American Society for Microbiology

Published: Jan. 3, 2024, 8 a.m.
High-fat diets promote peritoneal inflammation and augment endometriosis-associated abdominal hyperalgesia.

Immune dysfunction is one of the central components in the development and progression of endometriosis by establishing a chronic inflammatory environment. Western-style high-fat diets (HFD) have been linked to greater …

Published: Nov. 13, 2023, midnight
Mediterranean Diet and Oxidative Stress: A Relationship with Pain Perception in Endometriosis.

Endometriosis is a chronic and inflammatory disease associated with pelvic pain. Dietary changes may be therapeutic for chronic inflammatory processes, reducing visceral input. The aim was to evaluate the role …

Published: Sept. 27, 2023, midnight
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