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Suppression of endometriosis by miRNA-34a via inhibition of matrix metalloproteinase-2: An alternative pathway to impede invasion.

Matrix metalloproteinases (MMPs) cleave proteins of extracellular matrix thus facilitating cellular invasion and cancer progression. High MMP-2 activity is frequently reported in several diseases including endometriosis and cancer. Endometriosis, though …

Published: Feb. 24, 2025, midnight
Endometriosis Presenting as a Rare Cause of Intestinal Perforation: A Case Report With Literature Review.

This case report details a 39-year-old woman with a history of endometriosis who presented with severe abdominal pain, vomiting, and nausea, leading to a diagnosis of intestinal perforation caused by …

Published: Feb. 23, 2025, midnight
Primary Low-Grade Endometrial Stromal Sarcoma of the Ovary Arising From Endometriosis: A Case Report.

Low-grade endometrial stromal sarcoma (LGESS) is a rare mesenchymal tumor of female genital tract malignancies. While it primarily arises in the uterus, extrauterine cases, including those originating in the ovary, …

Published: Feb. 23, 2025, midnight
The effect of combined oral contraceptive pills on angiogenesis in endometriotic lesions.

Neoangiogenesis is necessary for adhesion and invasion of endometriotic lesions. We hypothesize that by blocking angiogenetic pathways we can suppress endometriosis. Oral contraceptive pills (OCs) are routinely used in endometriosis …

Published: Feb. 21, 2025, midnight
Endometriosis: A new perspective on epigenetics and oxidative stress.

As a complex chronic gynecological disorder characterized by multifaceted etiology involving genetics, environment, immunity and inflammation, endometriosis (EM) has long been a significant concern for women of reproductive age worldwide. …

Published: Feb. 21, 2025, midnight
Severe endometriosis during pregnancy: incarcerated gravid uterus with concurrent placenta previa.

Published: Feb. 21, 2025, midnight
Women's experience, satisfaction, and continuation with the levonogestrel-containing intrauterine system: A cross-sectional study.

The levonorgestrel-containing intrauterine system (LNG-IUS) is a safe, long-acting, reversible contraceptive method. This study aimed to examine women's experiences, satisfaction, and continuation with the levonorgestrel-containing intrauterine system. This cross-sectional study …

Published: Feb. 20, 2025, 12:15 a.m.
COVID-19 and our understanding of vitamin D and immune function.

The interaction between vitamin D and the immune system is perhaps the most well recognised extraskeletal facet of vitamin D, encompassing early studies of therapy for TB and leprosy through …

Published: Feb. 20, 2025, midnight
Cell Migration in Endometriosis Responds to Omentum-Derived Molecular Cues Similar to Ovarian Cancer.

Endometriosis is common and poses significant morbidity of lasting impact to young, pre-menopausal women, while ovarian cancer is a lethal gynecologic condition. Both conditions need better treatment. The human omentum …

Published: Feb. 20, 2025, midnight
The Role of Psychologists in Treating Pelvic Pain Conditions.

Patients with pelvic floor disorders may experience a wide range of symptoms affecting one or more compartments of the pelvic floor (anterior/urinary, apical/reproductive, and posterior/gastrointestinal). Disorders affecting the pelvic organs …

Published: Feb. 20, 2025, midnight
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