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Single-cell analysis identifies distinct macrophage phenotypes associated with prodisease and proresolving functions in the endometriotic niche.

Endometriosis negatively impacts the health-related quality of life of 190 million women worldwide. Novel advances in nonhormonal treatments for this debilitating condition are desperately needed. Macrophages play a vital role …

Published: Sept. 10, 2024, midnight
Three-dimensional virtual histology of the rat uterus musculature using micro-computed tomography.

Contractions of the uterus play an important role in menstruation and fertility, and contractile dysfunction can lead to chronic diseases such as endometriosis. However, the structure and function of the …

Published: Sept. 10, 2024, midnight
Adenomyosis: An Update Concerning Diagnosis, Treatment, and Fertility.

This review article aims to summarize current tools used in the diagnosis of adenomyosis with relative pharmacological and surgical treatment and to clarify the relative association between adenomyosis and infertility, …

Published: Sept. 3, 2024, midnight
Endometrial E-cadherin and N-cadherin Expression during the Mid-Secretory Phase of Women with Ovarian Endometrioma or Uterine Fibroids.

Endometriosis and uterine fibroids are benign conditions frequently linked to subfertility/infertility. Recent research has highlighted the importance of epithelial-mesenchymal transition between embryonic and endometrial cells in the context of embryo …

Published: Aug. 29, 2024, midnight
Ruptured Ectopic Pregnancy, Ovarian Torsion, Dermoid Cyst, Leiomyomata, and Endometriosis: A Case Report of a Pelvic Quintet.

The chances of a female of reproductive age presenting with a ruptured ectopic pregnancy are relatively low. Ectopic pregnancies make up 1-2% of all pregnancies and 20% of ectopic ruptures. …

Published: Aug. 14, 2024, midnight
Predicting nutrition and environmental factors associated with female reproductive disorders using a knowledge graph and random forests.

Female reproductive disorders (FRDs) are common health conditions that may present with significant symptoms. Diet and environment are potential areas for FRD interventions. We utilized a knowledge graph (KG) method …

Published: April 17, 2024, midnight
Magnetic Resonance-Guided Focused Ultrasound Surgery for Gynecologic Indications.

Magnetic resonance-guided focused ultrasound surgery (MRgFUS) appears to be an effective and safe treatment for uterine fibroids and adenomyosis, particularly in women who wish to preserve fertility. In abdominal wall …

Published: March 27, 2024, midnight
Elagolix Sodium Salt and Its Synthetic Intermediates: A Spectroscopic, Crystallographic, and Conformational Study.

Elagolix sodium salt is the first marketed orally active non-peptide gonadotropin-releasing hormone receptor antagonist (GnRHR-ant) for the management of hormone dependent diseases, such as endometriosis and uterine fibroids. Despite its …

Published: May 3, 2023, midnight
Genetic and Epidemiological Similarities, and Differences Between Postoperative Intraperitoneal Adhesion Development and Other Benign Fibro-proliferative Disorders.

Intraperitoneal adhesions complicate over half of abdominal-pelvic surgeries with immediate, short, and long-term sequelae of major healthcare concern. The pathogenesis of adhesion development is similar to the pathogenesis of wound …

Published: Sept. 13, 2021, midnight
Magnetic Resonance Imaging of Uterine Cervix: A Pictorial Essay.

Uterine cervix is the lower constricted part of uterus which is best evaluated by magnetic resonance imaging (MRI) due to its higher soft tissue and contrast resolution. The cervical cancer …

Published: Aug. 4, 2021, midnight
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