Chronic pelvic pain (CPP) is a common and burdensome symptom in women yet current clinical management frequently leaves many with persistent pain. The Translational Research in Pelvic Pain (TRiPP) project …
Endometriosis is a chronic inflammatory disorder with poorly understood mechanisms. Inflammatory proteins are hypothesized to play a causal role, but evidence remains limited. We performed a 2-sample Mendelian randomization study …
While plausible mechanisms exist for an association between endometriosis and hypertriglyceridemia, prior studies have shown inconsistent findings, possibly due to the inability to assess endometriosis severity or subtypes.
Endometriosis (EMS), a chronic inflammatory disease affecting approximately 10% reproductive aged women, remains etiologically unclear. This study aims to investigate the role and underlying mechanisms of frizzled class receptor 7 …
Adenomyosis is a common gynecological disorder characterized by the presence of endometrial tissue in the myometrium, causing chronic pelvic pain and abnormal bleeding. Although dysregulated microRNAs (miRNAs) in stromal cells …
Endometriosis is a prevalent gynecological disorder, with its pathogenesis potentially linked to oxidative stress. Carotenoids, as natural antioxidants, may play a role in its prevention. This study aimed to investigate …
Adenomyosis and endometriosis are chronic gynecological disorders with overlapping mechanisms and symptoms, both linked to impaired sexual health and relationships. This study compared sexual function, sexual quality of life, and …
Ferroptosis, as an iron-dependent programmed cell death, plays a significant role in reproductive system diseases. It's involved in the pathological processes of various reproductive system diseases by affecting the survival …
Inflammation-driven mechanisms in endometrial cancer: pathways from inflammatory microenvironment remodeling to immune escape Frontiers
Endometriosis is a chronic inflammatory condition, typically associated with pelvic pain and menorrhagia, affecting 10% of women of reproductive age. Inflammation is known to contribute to pregnancy complications, including preterm …