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Cancer Risk Profile of the Levonorgestrel-Releasing Intrauterine Device: A Narrative Review.

Background/Objectives: The levonorgestrel-releasing intrauterine device (LNG-IUD) is widely used as a long-acting reversible contraceptive and as a therapeutic option for heavy menstrual bleeding, endometriosis, adenomyosis, and endometrial hyperplasia. Although its …

Published: July 23, 2026, midnight
Glycolytic Reprogramming in Endometriosis: Biological Basis and Emerging Targets for Disease-Modifying Therapy.

Endometriosis is a chronic gynecological disease affecting approximately 10% of women of reproductive age and up to 40% of women with infertility, with a significant impact on quality of life …

Published: July 23, 2026, midnight
Perceived Access to Endometriosis Care Among Hispanic Women: A Cross-Sectional Survey.

Primary objective We evaluated perceived access to endometriosis-related care among Hispanic and non-Hispanic women with endometriosis. Secondary objectives We compared referral experiences, financial barriers, geographic access, and specialist access between …

Published: July 23, 2026, midnight
The Therapeutic Role of Dienogest in Endometriosis-Associated Pain: From Basics to Clinics.

The most common symptom of endometriosis is pain. The pathogenesis of endometriosis-associated pain remains unclear. In this review, we illustrate the pathogenesis of endometriosis-associated pain and the mechanisms of dienogest …

Published: July 23, 2026, midnight
The Molecular and Cellular Mechanisms of Melatonin: From Physiological Actions to Clinical Applications in Reproductive Medicine.

Melatonin has evolved from its classical role as a pineal-derived circadian regulator to a molecule increasingly recognized for its mitochondrial and cytoprotective functions. This review examines the molecular mechanisms and …

Published: July 22, 2026, midnight
Integrating single-cell and bulk transcriptomic perturbation resources reveals complementary therapeutic spaces for drug repurposing.

Transcriptome-based drug repurposing can accelerate therapeutic discovery, but is limited by fragmented resources, inconsistent quality control, and reliance on single perturbation databases. We developed CDRPipe ( C omputational D rug …

Published: July 22, 2026, midnight
Associations of health and lifestyle factors with multidimensional quality of life among women with endometriosis: a cross-sectional study.

Endometriosis is a chronic disease associated with pain, fertility difficulties, and reduced quality of life (QoL). Beyond clinical symptoms, health-related and lifestyle behaviors may influence the long-term impact of the …

Published: July 22, 2026, midnight
p53-mediated epigenetic regulation in the pathogenesis of endometriosis.

Endometriosis (EMs) is a common gynecological disorder affecting reproductive‑aged women, characterized by ectopic endometrial growth and chronic pelvic pain that severely impairs quality of life. Although its pathogenesis remains incompletely …

Published: July 21, 2026, midnight
Can AI speak endo? A multi-platform evaluation of large language models against ESHRE endometriosis guidelines.

How do the three most widely accessible large language models perform in terms of accuracy, consistency, and reliability when answering clinically relevant questions derived from the 2022 ESHRE guideline on …

Published: July 21, 2026, midnight
Menopause and Endometriosis - Symptoms and Risk of Malignant Transformation: A Systematic Review of the Literature.

To review the evidence concerning the clinical presentation of endometriosis in postmenopausal women and the associated risk of malignant transformation.

Published: July 21, 2026, midnight
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