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Multi-locus high-risk alleles association from interleukin's genes with female infertility and certain comorbidities.

Objective There is evidence that cytokine genes' single nucleotide polymorphisms could be the reasons behind female infertility. This study aimed to identify the role for Interleukin33 rs1048274 (G > A) …

Published: Nov. 23, 2024, midnight
M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits.

Endometriosis is a common gynecologic condition that causes chronic life-altering symptoms including pain, infertility, and elevated cancer risk. There is an urgent need for new non-hormonal targeted therapeutics to treat …

Published: Nov. 22, 2024, midnight
The causality between gut microbiota and endometriosis: a bidirectional Mendelian randomization study.

Observational studies and animal experiments had suggested a potential relationship between gut microbiota abundance and pathogenesis of endometriosis (EMs), but the relevance of this relationship remains to be clarified.

Published: Nov. 22, 2024, midnight
Identification of key genes associated with endometriosis and endometrial cancer by bioinformatics analysis.

Endometriosis (EMS) is acknowledged as a risk factor for the development of endometrial cancer (EC), although the precise molecular mechanisms that underpin this association have yet to be fully elucidated. …

Published: Nov. 22, 2024, midnight
Association between chronic stress-related amygdala metabolic activity and lymph node metastasis in endometrial cancer - Nature.com

Association between chronic stress-related amygdala metabolic activity and lymph node metastasis in endometrial cancer Nature.com

Published: Nov. 18, 2024, 6:27 a.m.
Causal Link between Gut Microbiota and Infertility: A Two-sample Bidirectional Mendelian Randomization Study.

To investigate the associations of the gut microbiota with reproductive system diseases, including female infertility, male infertility, polycystic ovary syndrome (PCOS), primary ovarian failure, endometriosis, uterine fibroids, uterine polyps, sexual …

Published: Nov. 18, 2024, midnight
A bird-eye view of diaphragmatic endometriosis: current practices and future perspectives.

Diaphragmatic endometriosis is one of the most common localization of extra-pelvic endometriosis and may cause debilitating symptoms such as cyclic shoulder pain, right upper abdominal pain, and right-sided chest pain. …

Published: Nov. 15, 2024, midnight
Association between triglyceride glucose index and endometriosis in adults in the United States: A comprehensive study from the National Health and Nutrition Examination Survey (NHANES).

The triglyceride glucose (TyG) index has been well recognized as a reliable marker of insulin resistance and substantially correlated with the pathogenesis and progression of hypertension and cardiovascular diseases. However, …

Published: Nov. 13, 2024, midnight
Relationship between Cardiometabolic index and endometriosis in a US nationally representative sample: results from NHANES 1999-2006.

Endometriosis is an estrogen-dependent gynecological endocrine condition and a systemic inflammatory disease associated to improper lipid metabolism and increased cardiovascular risk. The Cardiometabolic Index (CMI) is a novel indicator representing …

Published: Nov. 12, 2024, midnight
Co-occurrence of Unicornuate Uterus with Non-Communicating Functioning Rudimentary Horn and VACTERL Association - A Case Report.

The co-occurrence of a unicornuate uterus with a non-communicating, functioning rudimentary horn (UUNCFRH) and VACTERL association represents an extremely rare condition, with only three similar cases reported in the literature.

Published: Nov. 11, 2024, midnight
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