Latest Articles

Associations of Lipid Metabolism Abnormalities and Obesity With Endometriosis-Associated Ovarian Cancer.

To investigate the differences in lipid metabolism and obesity between patients with ovarian endometrioid carcinoma (OEC) and ovarian clear cell carcinoma (OCCC), both of which are classified as endometriosis-associated Type …

Barriers affecting medication adherence to dienogest among patients with ovarian endometriosis: a qualitative study.

To explore barriers affecting medication adherence (e.g., missed doses, forgotten doses, or discontinuation) among patients with Ovarian Endometriosis (OE) using the Capability, Opportunity, Motivation - Behaviour (COM-B) behavioural change model …

Rethinking estrogen receptor β in EAOC: a synergistic modulator in a genomically informed landscape.

HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma.

Ovarian clear cell carcinoma (CCC) is an aggressive subtype of ovarian cancer that is resistant to conventional chemotherapy, resulting in poor prognosis. CCC develops from endometriosis, which exposes tumor cells …

Metabolism-Regulating Microspheres: Design Principles, Therapeutic Applications Across Multisystem Diseases, and Future Perspectives.

Metabolism-regulating microspheres have evolved from conventional drug carriers into active platforms capable of spatiotemporally reprogramming pathological metabolic networks. Chronic diseases are increasingly understood to be driven by metabolic dysregulation, highlighting …

Beneficial Effects of Fisetin, a Senotherapeutic Compound, in Women's Reproductive Health and Diseases: Evidence from In Vitro to Clinical Studies.

Fisetin is a naturally occurring flavonoid, a type of polyphenol found in fruits and vegetables such as strawberries, apples, persimmons, and onions. It has gained increasing attention for its antioxidant …

Optimal Laparoscopic Surgical Technique for Preserving Fertility and Ovarian Reserve in Patients with Endometrioma: A Systematic Review and Bayesian Network Meta-Analysis of Randomized Controlled Trials.

This systematic review and Bayesian network meta-analysis aimed to evaluate the comparative efficacy and safety of various laparoscopic techniques for endometrioma management, focusing on their impact on fertility outcomes and …

Pure non-gestational ovarian choriocarcinoma in a postmenopausal woman coexisting with a clear cell adenofibroma and endometriosis foci: A case report and review of the literature.

Ovarian germ cell tumours are uncommon, with choriocarcinoma being the rarest of them. Among choriocarcinomas, the non-gestational type occurs mainly in premenarchal women, although cases have been described in postmenopausal …

Biomaterials for Reproductive Restoration: Translating Engineering Innovations.

Advances in cancer therapy, delayed parenthood, and an increasing number of reproductive disorders have intensified the need for the effective preservation of fertility. However, current clinical strategies such as ovarian …

Average oocyte quality index as a method for scoring dysmorphic oocytes in women with ovarian endometrioma undergoing in vitro fertilization and its correlation with ovarian reserve.

This study investigated whether the average oocyte quality index (AOQI), used as a dysmorphic oocyte scoring system, is higher in women with ovarian endometrioma than in those with unexplained infertility …