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Transfer RNA-derived small RNAs in female reproductive disorders: emerging roles and clinical implications.

Female reproductive disorders present significant challenges worldwide. Transfer RNA-derived small RNAs (tsRNAs), a structurally diverse class of non-coding RNAs mainly comprising tRNA halves (tiRNAs) and tRNA-derived fragments (tRFs), have emerged …

Published: April 29, 2026, midnight
Multi-ancestry genome-wide association and integrated multi-omics analyses of endometriosis and its clinical manifestations.

Endometriosis is a chronic systemic disease affecting ~10% of women, yet its genetic basis and molecular mechanisms remain poorly understood. Hence, here we conducted a genome-wide association study of endometriosis …

Published: April 29, 2026, midnight
Purdue Pharma faces sentencing in $7B opioid settlement case - newscentermaine.com

Purdue Pharma faces sentencing in $7B opioid settlement case newscentermaine.com

Published: April 28, 2026, 9:44 p.m.
A man faces felony charges after police say he fled the scene of a crash in Bangor - newscentermaine.com

A man faces felony charges after police say he fled the scene of a crash in Bangor newscentermaine.com

Published: April 27, 2026, 4:10 p.m.
Endocrine roles of vitamin D in female reproduction: Mechanisms and clinical implications.

Vitamin D a fat-soluble steroid hormone signals through Vitamin D Receptors (VDRs) located throughout the ovaries, uterus, placenta, hypothalamus, and pituitary gland, influencing immune regulation and female reproductive physiology. This …

Published: April 27, 2026, midnight
NET-DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy-Mediated Anoikis Resistance in Endometriosis.

Endometriosis (EMs) features ectopic implantation of endometrial stromal cells (EESCs) and strong anoikis resistance, yet how inflammatory signals reprogram mitochondrial function remains unclear. Here, neutrophil extracellular traps (NETs), particularly their …

Published: April 27, 2026, midnight
Nursing care for patients with endometriosis in Aotearoa New Zealand: a survey study.

Endometriosis is a chronic condition where patients face challenging care journeys. There is minimal literature regarding perspectives of nurses on their approach to caring for endometriosis patients.

Published: April 27, 2026, midnight
Lena Dunham shares how she made peace with the possibility of welcoming kids differently than she imagined - MSN

Lena Dunham shares how she made peace with the possibility of welcoming kids differently than she imagined MSN

Published: April 26, 2026, 4:23 p.m.
A comprehensive treatment algorithm for chronic pelvic pain patients: A perspective review and future guidelines.

Chronic pelvic pain is one of the most prevalent syndromes in family medicine, gynecology, and urology. Chronic pelvic pain patients are often misdiagnosed and have unnecessary prolonged suffering. Both misdiagnosis …

Published: April 25, 2026, midnight
SIRT1-mediated deacetylation of HMGB1 promotes the progression of endometriosis by regulating autophagy.

Published: April 25, 2026, midnight
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