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Depot medroxyprogesterone acetate and the risk for developing an intracranial meningioma.

Several investigations have reported on the increased risk of meningioma following depot medroxyprogesterone acetate (DMPA) treatment. An extensive PubMed search was conducted evaluate systematic reviews, propensity-matched studies and case-control studies …

Published: Sept. 21, 2026, midnight
Obstetric and Neonatal Outcomes in Deep Infiltrating Versus Superficial Endometriosis: A Retrospective Cohort Study.

To compare obstetric and neonatal outcomes between women with surgically confirmed deep infiltrating endometriosis (DIE) and superficial endometriosis, focusing on lesion-specific risk profiles. This retrospective cohort study included women with …

Published: Sept. 21, 2026, midnight
Methodological Pitfalls in Endometriosis Biospecimen Research: Lessons From MAP4K4 Expression Studies.

Endometriosis is a chronic inflammatory condition affecting 10% of reproductive-age women. Current treatments remain limited and non-curative. While its biology is largely informed by human biospecimens, sample heterogeneity and methodological …

Published: Sept. 21, 2026, midnight
Evaluating potential risk factors linked to endometriosis: Evidence from a Mendelian randomization study.

Earlier examinations of how risk factors relate to endometriosis (EMT) have largely depended on observational designs, which arrived at conflicting conclusions. The present approach seeks to probe the causal association …

Published: Sept. 20, 2026, midnight
The Meiotic Spindle, Mechanisms of Chromosome Segregation and Aneuploidy in Aging Human Oocytes: An Update Review.

The meiotic spindle is essential for accurate chromosome segregation during oocyte maturation and fertilization, and its alteration might be considered a major contributor to age-related aneuploidy and reproductive failure. Spindle …

Published: Sept. 20, 2026, midnight
Neuroimmune fitness in endometriosis: decoding the adaptive neural circuits that sustain lesion persistence, fibrosis, and chronic pain.

Endometriosis is a chronic inflammatory disease characterized by substantial heterogeneity in pain, lesion behavior, and treatment response. Although hormonal and surgical therapies can reduce disease activity and symptoms, their effects …

Published: Sept. 19, 2026, midnight
Mediterranean Diet Adherence and Endometriosis Symptoms: Implications for Nutritional Management.

Endometriosis is a chronic inflammatory disease significantly impairing quality of life (QoL). While the Mediterranean diet (MD) may modulate inflammation, evidence regarding its relationship with symptom burden is limited. This …

Published: Sept. 18, 2026, midnight
Ovarian Precancerous Lesions and Their Molecular Landscape: A Structured Scoping Review Focused on STIC and Related Precursors of Epithelial Ovarian Cancer.

Ovarian cancer remains one of the deadliest gynecologic malignancies because of late-stage diagnosis, biological heterogeneity, and the lack of effective early detection strategies. Epithelial ovarian cancer (EOC) comprises several histotypes, …

Published: Sept. 18, 2026, midnight
Lifestyle factors and symptom burden in endometriosis: an exploratory mixed-methods analysis of nutrition, physical activity, and psychosocial well-being.

Endometriosis affects approximately 10% of reproductive-age women worldwide, with symptom burden significantly impacting quality of life. While current treatment guidelines focus primarily on hormonal and surgical interventions, the role of …

Published: Sept. 17, 2026, midnight
The Pathogenesis of Epithelial Ovarian Cancer.

Epithelial ovarian cancer is not a single disease but a group of biologically distinct malignancies that include serous (high-grade and low-grade), endometrioid, clear cell, and mucinous carcinomas, along with other …

Published: Sept. 17, 2026, midnight
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