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Estrogens hypersensitivity syndrome in endometriosis.

Objectives. The aim of the study was to develop a diagnostic method for estrogen hypersensitivity syndrome in proliferative benign diseases of the female reproductive system. Using the example of endometriosis, …

Published: Sept. 19, 2026, midnight
Endometriosis from Initiation to Innovation: Immune Microenvironments, Clonal Lesion Biology, and the Emerging Therapeutic Pipeline.

Endometriosis is a chronic, estrogen-dependent inflammatory disease that, despite its benign histology, displays several cancer-relevant features, including clonal expansion, somatic alteration-associated lesion evolution, tissue invasion, apoptosis resistance, immune evasion, angiogenesis, …

Published: Sept. 19, 2026, midnight
Single-Cell RNA Sequencing Reveals Immune Dysregulation and Candidate Drug Targets in Endometriosis.

Endometriosis is a chronic inflammatory disorder affecting 5-10% of women of reproductive age and is associated with chronic pain and infertility. While research has mainly focused on local lesions, systemic …

Published: Sept. 19, 2026, midnight
Association between endometriosis and cardiovascular disease: a population-based cohort study.

The relationship between endometriosis and cardiovascular disease (CVD) risk remains unclear. This study aimed to evaluate the association between endometriosis and CVD risk, to examine whether the association was affected …

Published: Sept. 18, 2026, midnight
Mediterranean Diet Adherence and Endometriosis Symptoms: Implications for Nutritional Management.

Endometriosis is a chronic inflammatory disease significantly impairing quality of life (QoL). While the Mediterranean diet (MD) may modulate inflammation, evidence regarding its relationship with symptom burden is limited. This …

Published: Sept. 18, 2026, midnight
Gynecologic imaging errors and pitfalls: how to avoid misdiagnosis on pelvic MRI.

Pelvic magnetic resonance imaging (MRI) plays a pivotal role in evaluating gynecologic diseases, offering superior soft-tissue characterization, multiplanar imaging, and functional assessment compared to ultrasound and computed tomography. This article …

Published: Sept. 17, 2026, midnight
The Pathogenesis of Epithelial Ovarian Cancer.

Epithelial ovarian cancer is not a single disease but a group of biologically distinct malignancies that include serous (high-grade and low-grade), endometrioid, clear cell, and mucinous carcinomas, along with other …

Published: Sept. 17, 2026, midnight
No broad PBMC cytokine-response fingerprint of endometriosis under PHA-stimulated culture conditions: A 27-plex case-control study.

Endometriosis is associated with immune dysregulation yet circulating cytokine measurements have shown limited discriminatory value. We investigated whether peripheral blood mononuclear cells (PBMCs) from women with endometriosis exhibit altered basal …

Published: Sept. 17, 2026, midnight
Curcumin Alleviates Endometriosis in Sexually Mature Female Mice by Targeting PKA and Inhibiting De Novo Estrogen Synthesis.

Background: Endometriosis is an estrogen-dependent disorder with limited treatment options. The precise molecular targets of curcumin and its effects on local estrogen synthesis in this disease remain unclear. Methods: We …

Published: Sept. 17, 2026, midnight
Augmented Reality, Mixed Reality, Computer Vision, and Three-Dimensional Modeling in Fertility-Preserving Minimally Invasive Gynecologic Surgery: A Scoping Review with Narrative Synthesis.

Background and Objectives: Augmented reality (AR), mixed reality (MR), computer vision, artificial intelligence (AI), and three-dimensional (3D) modeling may be particularly relevant in fertility-preserving gynecologic surgery, where disease must be …

Published: Sept. 17, 2026, midnight
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