The appendix is involved in a diverse spectrum of inflammatory, infectious, benign, and malignant conditions that extend far beyond acute appendicitis. Although acute appendicitis remains the most common appendiceal emergency, …
The concept of ferroptosis debuted as a newly defined programmed cell death in 2012. Among programmed cell death mechanisms, ferroptosis stands out as being fundamentally dependent on iron. At the …
The follicular fluid (FF) microenvironment plays a critical role in oocyte maturation and embryo development, reflecting local ovarian activity and systemic metabolic status. While metabolic alterations in FF have been …
Online Health Communities (OHCs) are key platforms for people seeking medical information and social support. Individuals with persistent pain often use these communities to better understand their condition, share experiences, …
In 2024, the National Academies of Sciences, Engineering, and Medicine (NASEM) published a report entitled Advancing Research on Chronic Conditions in Women. A major purpose of this report was to …
Lactate is increasingly recognized not only as a metabolic end product of glycolysis but also as a signaling metabolite that links metabolic reprogramming to epigenetic and transcriptional regulation through protein …
Natural bioactive compounds, such as curcumin, polyphenols, and flavonoids are important in the prevention and treatment of lifestyle disorders like diabetes, cancer, and heart disease. Their immunomodulatory, antiviral, antioxidant, and …
Endometriosis is a benign and chronic disease characterized by inflammation of the endometrial tissue outside the uterus. Numerous physical therapy interventions have been studied to alleviate the related symptoms.
Calcitonin gene-related peptide (CGRP), a neuropeptide, has been implicated in autoimmune diseases, endometriosis, tumors, and primary headaches, including migraine. The development of a novel, fast-acting CGRP receptor antagonist administered via …
The female reproductive tract (FRT), particularly the vagina, has traditionally been regarded as a sterile environment. However, it is now recognized that the vagina is a complex, dynamic ecosystem dominated …