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Efficacy of probiotic supplementation in reducing primary dysmenorrhea: a double-blinded randomized controlled trial.

Primary dysmenorrhea is painful menstruation in the absence of pelvic pathology, whereas secondary dysmenorrhea is menstrual pain attributable to an underlying pelvic disease (e.g., endometriosis). Nonsteroidal anti-inflammatory drugs (NSAIDs) are …

Published: March 17, 2026, midnight
Uterine Anteroposterior Diameter as an Imaging Correlate of Dysmenorrhea Severity: Findings Across Symptom Based Clusters.

Adenomyosis and endometriosis are both recognized as etiological factors in the development of dysmenorrhea; however, their respective contributions to this condition remains ambiguous. This study aims to examine the distinct …

Published: March 16, 2026, midnight
International Clinical Practice Guidelines on Traditional Chinese Medicine Therapy for Dysmenorrhea: Development Protocol.

Traditional Chinese medicine (TCM) functions according to the concepts of "holism" and treatment based on syndrome differentiation, and it has achieved good clinical results in treating patients with dysmenorrhea, which …

Published: March 11, 2026, midnight
Potential Harm of the Use of the Word "Benign" in Gynecologic Care.

"Benign gynecologic conditions" is an umbrella term widely used to describe prevalent conditions such as endometriosis, adenomyosis, uterine fibroids, and genitourinary syndrome of menopause in clinical guidelines, research, reviews, and …

Published: March 11, 2026, midnight
Association between estrogen receptor alpha 36 expression and the risk of deep infiltrating endometriosis.

Deep infiltrating endometriosis (DIE) is a severe subtype of endometriosis, often associated with dysmenorrhea and significant diagnostic challenges. Conventional biomarkers, such as cancer antigen 125 (CA125), lack sufficient specificity for …

Published: March 11, 2026, midnight
[Endometriose i klinisk praksis].

Endometriosis is a chronic, estrogen-dependent inflammatory disorder affecting ~10% of reproductive-age women. It is underdiagnosed, with delays of 5-12 years. Symptoms include dysmenorrhea, chronic pelvic pain, dyspareunia, dyschezia, dysuria, fatigue, …

Published: March 9, 2026, midnight
Accessory Cavitated Uterine Malformation (ACUM): A Case Series.

Accessory Cavitated Uterine Malformation (ACUM) can be misdiagnosed as other uterine pathologies, such as Müllerian anomalies, adenomyosis, or fibroids. In the present case series, we report on data of eleven …

Published: March 6, 2026, midnight
Bladder Endometriosis as Part of Complex Pelvic Deep Endometriosis: Surgical Challenges and Outcomes in a Reference Center.

Objective: To analyze multiple aspects of advanced bladder endometriosis surgery, based on the experience of an endometriosis reference center. Methods: This retrospective/prospective study included 80 consecutive patients with deep bladder …

Published: March 5, 2026, midnight
The predictive diagnostic value of combined serum detection of CXCL12, VEGF, and CA125 for endometriosis.

This study aims to explore the application value of stromal cell-derived factor (CXCL12), vascular endothelial growth factor (VEGF) and carbohydrate antigen 125 (CA125) in the diagnosis, staging, and clinical manifestations …

Published: March 1, 2026, midnight
Association between body mass index and dysmenorrhea in women with endometriosis: a systematic review and meta-analysis.

Dysmenorrhea is a debilitating symptom in patients with endometriosis, contributing significantly to disease burden. While the relationship between body mass index (BMI) and dysmenorrhea in these patients is unclear, emerging …

Published: Feb. 27, 2026, midnight
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