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Reduced type 2 epithelial-mesenchymal transition serves as a risk factor for the progression from endometriosis to endometriosis-associated ovarian cancer.

Endometriosis-associated ovarian cancer (EAOC) is a rare subtype of ovarian cancer arising from the malignant transformation of endometriosis (EMS). Despite growing clinical awareness, its underlying pathogenic mechanisms are not fully …

Published: May 1, 2026, midnight
Bioinformatics analysis implicates ferroptosis and key hub genes in the pathogenesis of endometriosis.

Endometriosis (EMs) is a chronic gynaecological condition characterised by the ectopic growth of endometrial tissue; however, its molecular mechanisms remain insufficiently understood. Ferroptosis, an iron-dependent form of regulated cell death, …

Published: April 30, 2026, midnight
Advancing the frontiers of phytotherapy: a comprehensive review of botanical interventions targeting mitochondrial quality control to ameliorate endometriosis.

Endometriosis (EMs) is a gynecological disorder affecting women of reproductive age. It is characterized by the ectopic implantation and infiltration of endometrial-like tissue and is associated with significant effects on …

Published: April 29, 2026, midnight
NET-DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy-Mediated Anoikis Resistance in Endometriosis.

Endometriosis (EMs) features ectopic implantation of endometrial stromal cells (EESCs) and strong anoikis resistance, yet how inflammatory signals reprogram mitochondrial function remains unclear. Here, neutrophil extracellular traps (NETs), particularly their …

Published: April 27, 2026, midnight
Single-Cell Transcriptomic Profiling and Machine Learning Integration Unveil Stromal Cell Heterogeneity in Endometriosis.

Endometriosis (EMs) affects approximately 10% of reproductive-age women worldwide, yet its pathogenesis remains incompletely understood. Abnormal cell differentiation and somatic mutations in the ectopic endometrial microenvironment play critical roles in …

Published: April 23, 2026, midnight
Curcumin modulates the function of SPP1+ macrophages via NF-κB signaling to alleviate endometriosis.

Endometriosis is a complex gynecological disorder with prominent cellular heterogeneity, and its key pathogenic cell subsets and core molecular mechanisms remain elusive, which restricts the development of effective therapeutic strategies. …

Published: April 17, 2026, midnight
Obstructive Sleep Apnea and Female Reproductive Endocrine Diseases: A Mendelian Randomization and Mediation Analysis.

This study aimed to evaluate the potential causal association between obstructive sleep apnea (OSA) and the risk of female reproductive endocrine diseases (REDs), including polycystic ovary syndrome (PCOS), endometriosis (EMs), …

Published: April 16, 2026, midnight
LRP1 as a potential diagnostic and immunomodulatory target in endometriosis: evidence from multi-omics and single-cell analyses.

Endometriosis (EMS) is a common gynecological disease that seriously affects women's health and quality of life. However, the detailed dynamic cellular and molecular mechanisms underlying EMS pathogenesis remain largely unknown. …

Published: April 15, 2026, midnight
The effect of endometriosis on fertility: Results of the National Health and Nutrition Examination and Mendelian randomization analysis, 1999 to 2006.

This study aims to investigate the effect of endometriosis (EMs) on fertility and to assess the causal relationship between EMs and fertility using two-sample Mendelian randomization (MR). We conducted an …

Published: March 7, 2026, midnight
The predictive diagnostic value of combined serum detection of CXCL12, VEGF, and CA125 for endometriosis.

This study aims to explore the application value of stromal cell-derived factor (CXCL12), vascular endothelial growth factor (VEGF) and carbohydrate antigen 125 (CA125) in the diagnosis, staging, and clinical manifestations …

Published: March 1, 2026, midnight
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