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Gut microbiota as a key regulator in endometriosis: mechanisms, therapeutic opportunities, and future perspectives.

Endometriosis (EMs), a common and frequently occurring gynecological disease, is a major cause of chronic pelvic pain and infertility in women. Its pathogenesis remains unclear to date, and it is …

Published: Jan. 30, 2026, midnight
Oxidative Stress Mediated by Macrophages Promotes Angiogenesis and Early Development of Endometriosis.

Endometriosis is a hormone-dependent gynecological disease manifested by cyclic pelvic pain and female infertility. Although many studies have shown that neoangiogenesis plays an essential role in the development of early …

Published: Jan. 23, 2026, midnight
Burden analysis of uterine fibroids and endometriosis in reproductive-age women globally, in China, India, and the United States, 1990-2021.

Uterine fibroids and endometriosis are common benign gynecological diseases affecting the health of women of childbearing age, characterized by high incidence and recurrence rates. Despite the increasing global emphasis on …

Published: Jan. 13, 2026, midnight
Urinary microRNAs for the non-invasive diagnosis of endometriosis identified by next-generation sequencing and machine learning.

Endometriosis is a chronic gynecological disease associated with pain, infertility, and delayed diagnosis. Non-invasive biomarkers are urgently needed to facilitate earlier detection and reduce the reliance on diagnostic laparoscopy. MicroRNAs …

Published: Jan. 7, 2026, midnight
Malignant Transformation Associated with Endometrioid Adenocarcinoma of Abdominal Wall Endometriosis: A Case Report and Literature Review.

Endometriosis is a prevalent chronic gynecological disease, characterized by the growth of endometrial glands and stroma outside the uterus and by the presence of chronic inflammatory lesions. This condition is …

Published: Dec. 30, 2025, midnight
Dysregulated autophagy in endometriosis: molecular mechanisms, controversies, and clinical implications.

Endometriosis is one of the most common gynecological diseases in women and is still one of the most understudied diseases, affecting the daily lives of patients. Although the exact cause …

Published: Dec. 13, 2025, midnight
Coexistence of gynecological pathology with endometriosis and adenomyosis.

Both endometriosis and adenomyosis can impact quality of life. Endometriosis is a chronic, benign, condition characterized by the growth of endometrium outside the uterus, which affects ~10% of women from …

Published: Dec. 12, 2025, midnight
Circulating miRNA as diagnostic tools for gynecological diseases and their applications in biosensor development.

MicroRNAs (miRNAs) have emerged as robust biomarkers for diagnosing and prognosing gynecological diseases due to their disease-specific expression and remarkable stability in body fluids. Despite the inherent instability of RNA …

Published: Nov. 15, 2025, midnight
The Interaction of PELP1 With FHL2 Contributes to Ectopic Endometrial Stromal Cell Proliferation, Angiogenesis, and Inflammation in Endometriosis.

Endometriosis (EMS), a multifactorial and chronic benign gynecological disease characterized by ectopic endometrial growth, remains poorly understood in its pathogenesis. Proline, glutamic acid, leucine-rich protein 1 (PELP1), implicated in various …

Published: Oct. 30, 2025, midnight
Reframing Endometriosis: Interplay of NETs, Macrophages, and Lymphocytes at the Crossroads of Disease Progression, Infertility, and Malignant Transformation.

Endometriosis (ENDO) is a painful, chronic gynecological disease widely affecting women globally. While traditionally classified as a hormonal disorder, ENDO is now increasingly recognized as a multifaceted immune-mediated syndrome driven …

Published: Oct. 29, 2025, midnight
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