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Cyclin D2 --a potential biomarker in uterine corpus endometrial carcinoma through methylation chip and bioinformatic analysis - Frontiers

Cyclin D2 --a potential biomarker in uterine corpus endometrial carcinoma through methylation chip and bioinformatic analysis Frontiers

Published: June 19, 2025, 10:09 p.m.
Leveraging epigenetic aberrations in the pathogenesis of endometriosis: From DNA methylation to non-coding RNAs - Frontiers

Leveraging epigenetic aberrations in the pathogenesis of endometriosis: From DNA methylation to non-coding RNAs Frontiers

Published: June 9, 2025, 4:59 p.m.
LINE-1 ORF1p expression occurs in clear cell ovarian carcinoma precursors and is a candidate blood biomarker.

Long interspersed element 1 (LINE-1) retrotransposons are repetitive sequences that can move within the genome by an autonomous mechanism. To limit their mutagenic potential, benign cells restrict LINE-1 expression through …

Published: March 6, 2025, midnight
A novel mechanism of FTO modulating the progression of endometriosis through mediating the m6A methylation of GEF-H1 in a YTHDF1-dependent manner.

Endometriosis (EMs) is a condition characterized by the growth of endometrial tissue outside the uterine cavity. Although this condition is benign, it has cancer-like features. N6-methyladenosine (m6A) is a common …

Published: Feb. 25, 2025, midnight
Systematic review on the DNA methylation role in endometriosis: current evidence and perspectives.

Endometriosis appears to have a multilayered etiology, with genetic and epigenetic factors each contributing half of the pathogenesis. The molecular processes that underlie the onset of endometriosis are yet unclear, …

Published: Feb. 21, 2025, midnight
Hypomethylation of IL6ST promotes development of endometriosis by activating JAK2/STAT3 signaling pathway.

Endometriosis is a chronic inflammatory disorder characterized by presence of endometrial tissue outside the uterine cavity. Immunohistochemical analysis (IHC) revealed markedly elevated expression of IL6ST in endometrial tissue of patients …

Published: Jan. 16, 2025, midnight
ALKBH5 promotes autophagy and progression by mediating m6A methylation of lncRNA UBOX5-AS1 in endometriosis.

Long noncoding RNA (lncRNA) and N6-methyladenosine (m6A) methylation modification have recently been suggested as potential functional modulators in ovarian endometriosis, however, the function and mechanism of m6A-modified lncRNA in ovarian …

Published: Jan. 6, 2025, midnight
Quantification of Free Circulating DNA and Differential Methylation Profiling of Selected Genes as Novel Non-Invasive Biomarkers for Endometriosis Diagnosis.

Endometriosis is a chronic, estrogen-dependent disorder associated with the presence of endometrial cells mainly in the pelvic cavity, causing systemic immune inflammation, infertility, epigenetic dysregulation of differential DNA methylation, coelomic …

Published: Jan. 6, 2025, midnight
Methylation Changes Linked to Preeclampsia & Pregnancy Complications - Physician's Weekly

Methylation Changes Linked to Preeclampsia & Pregnancy Complications Physician's Weekly

Published: Jan. 3, 2025, 3 p.m.
Unveiling DNA Methylation: Early Diagnosis, Risk Assessment, and Therapy for Endometrial Cancer - Frontiers

Unveiling DNA Methylation: Early Diagnosis, Risk Assessment, and Therapy for Endometrial Cancer Frontiers

Published: Dec. 30, 2024, 11:50 p.m.
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