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Safety of current strategies to manage moderate to severe pain in patients with endometriosis.

Medical therapy is crucial in the long-term management of endometriosis, and its clinical efficacy must be balanced with a favorable safety profile.

Published: Aug. 25, 2025, midnight
Comparison of quality of life in patients with endometriosis undergoing treatment with progestins, oral contraceptives pills (OCP), and GnRH agonists.

The objective of this study was to compare the quality of life in patients with endometriosis undergoing treatment with progestins, OCPs, and GnRH agonists.

Published: Aug. 20, 2025, midnight
Disease Severity- and Hormonal Status-Dependent Alterations of EGF and MIF in the Serum of Endometriosis Patients.

Endometriosis is the extrauterine engraftment of endometrium-like tissue, causing chronic pain. Complex sensory-vascular-immune interactions, including growth factors, cytokines, and neuropeptides, are implicated in its pathophysiology, but the mechanisms remain unknown. …

Published: July 12, 2025, midnight
Reply to 'Critical appraisal of "Comparison of combined oral contraceptives and dienogest for endometriosis-associated pain"'.

Published: April 2, 2025, midnight
The effect of combined oral contraceptive pills on angiogenesis in endometriotic lesions.

Neoangiogenesis is necessary for adhesion and invasion of endometriotic lesions. We hypothesize that by blocking angiogenetic pathways we can suppress endometriosis. Oral contraceptive pills (OCs) are routinely used in endometriosis …

Published: Feb. 21, 2025, midnight
Critical appraisal of "Comparison of combined oral contraceptives and dienogest for endometriosis-associated pain".

Published: Feb. 18, 2025, midnight
Weighing up GnRH agonist therapy for endometriosis: outcomes and the treatment paradigm.

Endometriosis is a chronic inflammatory estrogen-dependent disease affecting 10% of women worldwide leading to chronic pelvic pain and infertility which may be treated clinically or surgically.

Published: Jan. 25, 2025, midnight
Clinical effectiveness of progestogens compared to combined oral contraceptive pills in the treatment of endometriosis: A systematic review and meta-analysis.

Endometriosis involves the growth of endometrium-like cells outside the uterus, affecting reproductive-aged women. Symptoms such as dysmenorrhea, pelvic pain, and infertility significantly impair quality of life. Among therapeutic options, progestogens …

Published: Jan. 23, 2025, midnight
Selective progesterone receptor modulators for the treatment of dysmenorrhea: an update.

Dysmenorrhea is a painful symptom associated with uterine contractions and menstrual bleeding and is treated by administering analgesic drugs. Since progesterone receptors (PRs) have a major role in regulating uterine …

Published: Jan. 14, 2025, midnight
Endometriosis and risk of depression among oral contraceptive users: a pooled analysis of cohort studies from 13 countries.

Does endometriosis affect the mental health of women using oral contraceptives?

Published: Jan. 12, 2025, midnight
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