Our study focused on fabricating and characterizing a crocin in situ forming hydrogel for endometriosis treatment. An artificial neural network (ANN)-based machine learning (ML) approach was employed to determine the …
Müllerian adenosarcoma (MA) is a rare malignant tumor of the female reproductive system. Owing to the limited number of clinical cases and the absence of characteristic clinical manifestations, its clinical …
Endometriosis is an estrogen-driven, inflammatory disorder affecting ~10% of menstruators, causing severe pain. Current treatments that reduce estrogen or inflammation have inconsistent efficacy and poor tolerability. Therapies identified via drug-repositioning …
Obesity is a major global public health concern closely linked to the development and progression of various gynaecological disorders, particularly polycystic ovary syndrome (PCOS) and endometrial cancer. Incretins, a group …
Endometriosis treatment requires women to navigate complex, preference-sensitive decisions. Patient Decision Aids (PtDAs) help patients make value-aligned choices. However, the scope and quality of digital PtDAs for endometriosis, and the …
Endometriosis is often diagnosed several years after the first onset of symptoms; however, the duration of this delay may vary depending on the population studied, the assessment starting point, and …
Women's reproductive and endocrine disorders including Polycystic Ovary Syndrome (PCOS), endometriosis, thyroid disorders, infertility, and pregnancy-related complications remain a major global health burden. These conditions are especially difficult to manage …
Interleukin 37 (IL‑37), a member of the IL‑1 family, is recognized as an anti‑inflammatory cytokine. The anti‑inflammatory properties of recombinant human (rh)IL‑37 have been confirmed in vitro and its protective …
Myfembree, a fixed-dose combination of relugolix, estradiol, and norethindrone acetate, is approved for premenopausal women with heavy menstrual bleeding associated with uterine fibroids and moderate to severe pain associated with …
A woman in her 20s presented with severe progressive dysmenorrhoea that began within 1-2 years of menarche, was refractory to medical therapy and required repeated emergency department visits for parenteral …