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miR-769-5p inhibits cellular behaviors associated with endometriosis progression by directly targeting follistatin in vitro.

The pathogenesis of endometriosis (EM) remains intricate and multifactorial. This study aimed to investigate the biological functions of microRNA-769-5p (miR-769-5p) in an in vitro model of EM. Serum was obtained …

Published: April 30, 2026, midnight
Research progress and future directions in circadian rhythms for uterine‑related diseases (Review).

Circadian rhythms are ~24 h endogenous rhythms driven by both central and peripheral clocks, with their core mechanism being a transcription‑translation feedback loop mediated by master clock genes. The present …

Published: April 30, 2026, midnight
Laparoscopically guided transversus abdominis plane block versus local wound infiltration analgesia in laparoscopic surgery for peritoneal endometriosis: A prospective randomized controlled double-blinded LTAP-trial.

Endometriosis patients often suffer from more severe pain in association with surgical procedures. The aim of this study was to investigate whether laparoscopically guided transversus abdominis plane block (LTAP) offers …

Published: April 30, 2026, midnight
Surgical management of catamenial pneumothorax: a systematic review.

Catamenial pneumothorax is a rare manifestation of thoracic endometriosis syndrome and is associated with a high risk of recurrence despite surgical intervention. Increasingly, multimodal strategies combining thoracic surgery with adjunctive …

Published: April 30, 2026, midnight
Endometriosis in Adolescents: A Literature Review.

Endometriosis is a chronic gynecological disorder that affects approximately 10% of women of reproductive age. In adolescents, it frequently remains underdiagnosed due to the heterogeneity of its clinical presentation. Pelvic …

Published: April 30, 2026, midnight
Uterine and Sigmoid Colon Perforation Following Hysteroscopy-Guided Microwave Endometrial Ablation (MEA) in a Patient With a Bicornuate Uterus and Multiple Myomas: A Case Report.

In Japan, the microwave endometrial ablation system (MEA, Microsulis PLC, Waterlooville, UK) is the most widely used device for endometrial ablation and is considered a minimally invasive, uterus-preserving treatment for …

Published: April 29, 2026, midnight
[Investigation of pharmacological regimens combined with focused ultrasound ablation surgery for alleviating dysmenorrhea in extrinsic adenomyosis].

Objective: To investigate optimal long-term medication regimens combined with focused ultrasound ablation surgery (FUAS) for alleviating dysmenorrhea in patients with extrinsic adenomyosis. Methods: A retrospective research enrolled patients with extrinsic …

Published: April 29, 2026, midnight
Transfer RNA-derived small RNAs in female reproductive disorders: emerging roles and clinical implications.

Female reproductive disorders present significant challenges worldwide. Transfer RNA-derived small RNAs (tsRNAs), a structurally diverse class of non-coding RNAs mainly comprising tRNA halves (tiRNAs) and tRNA-derived fragments (tRFs), have emerged …

Published: April 29, 2026, midnight
Clinically Validated Leptin Receptor as a Target for Liposomal Delivery of Metformin in Endometriosis Therapy.

Endometriosis is a common, estrogen-driven chronic gynecologic disorder defined by the ectopic growth of endometrial-like tissue within the peritoneal cavity. Existing treatment options, primarily surgery and hormonal therapy, are limited …

Published: April 29, 2026, midnight
Benefits of minimal ethanol volume and retention without removal in transvaginal ethanol sclerotherapy for endometriomas.

This study aims to introduce an effective protocol for transvaginal ethanol sclerotherapy, focussing on the aspiration of viscous cystic content and the amount of ethanol instilled in the cystic cavity …

Published: April 29, 2026, midnight
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