Female reproductive disorders present significant challenges worldwide. Transfer RNA-derived small RNAs (tsRNAs), a structurally diverse class of non-coding RNAs mainly comprising tRNA halves (tiRNAs) and tRNA-derived fragments (tRFs), have emerged …
Reproductive health unfolds across the lifespan, and individuals may move through diverse pathways - including infertility, chronic gynecologic conditions such as endometriosis, pregnancy complications, assisted reproduction or gestational carriage. These …
Endometriosis is a chronic, estrogen-dependent, and heterogeneous gynecologic disorder associated with persistent pain, infertility, and substantial impairment in quality of life (QoL), necessitating individualized and evidence-based management. This narrative review …
Endometriosis is a chronic estrogen-dependent disorder affecting approximately 10% of women of reproductive age. Increasing epidemiological and molecular evidence indicates that it may represent a precursor condition for a subset …
Background/Objective: RNA modifications, including N6-methyladenosine (m6A), 5-methylcytosine (m5C), 7-methylguanosine (m7G), N1-methyladenosine (m1A), pseudouridine (Ψ), N4-acetylcytidine (ac4C), 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) and adenosine-to-inosine (A-to-I) editing, constitute a critical layer of post-transcriptional regulation that …
The Colony-Stimulating Factor 3 Receptor (CSF3R), the receptor for granulocyte colony-stimulating factor (G-CSF), has expanded from a hematopoietic regulator to a multifunctional signalling molecule with significant relevance in gynaecological biology. …
Clear cell adenocarcinoma arising from abdominal wall endometriosis (AWE) is extremely rare. We report a case of a 60-year-old woman with a history of cesarean section and surgically treated AWE. …
Vulvodynia is a chronic vulvar pain condition significantly affecting the quality of life. Its multifactorial etiology is not fully understood, and comprehensive pooled data on associated risk factors are lacking …
This study aimed to identify adolescent-specific risk factors for endometriosis onset and postoperative recurrence to facilitate early identification and risk stratification.