Endometriosis progression is driven by oxidative stress and excessive angiogenesis within an inflammatory microenvironment. To overcome these challenges, we designed ROS/pH dual-responsive Alpelisib-loaded nanoparticles (Alp@TAT-AT7-NPs) functionalized with an anti-NRP1 peptide …
Psychological distress and reduced health-related quality of life are common among women with endometriosis, particularly when the condition is accompanied by chronic pain. Psychological flexibility (PF), a core process in …
Endometriosis (EMs) is characterized by dysregulated persistence and enhanced invasiveness of ectopic endometrial cells. Current treatment strategies remain limited by high recurrence rates and considerable adverse effects. Although iron overload …
Chronic pelvic pain (CPP) affects over 25% of women, with endometriosis being a predominant cause. Central sensitization, particularly pelvic and perineal pain central sensitization (PPCS), is increasingly recognized as a …
Ovarian carcinosarcoma typically comprises high-grade carcinoma and sarcoma components. We report a case of a woman in her 40s with endometriosis-associated ovarian carcinosarcoma exhibiting an unusual presentation of well-differentiated adenocarcinoma …
Goserelin is a gonadotropin-releasing hormone (GnRH) agonist with a long history of clinical application and well-established efficacy and safety profile. Its mechanism of action centers on sustained GnRH receptor desensitization, …
Surgery represents a primary treatment option in selected cases of bowel endometriosis (BE), particularly in patients with significant symptoms or those unresponsive to medical therapy, and effectively improves patients' quality …
Background/Objectives: Endometriosis is a chronic condition affecting women of reproductive age. Its symptoms have a negative impact on the quality of life and fertility of many women in the population. …
Treatment for women with endometriosis is only partially or temporarily effective. Moreover, medical hormonal treatment is associated with debilitating side effects and interferes with fertility, while surgery has a relatively …
Progestins are widely used for endometriosis with proven efficacy and favorable safety. Their microvascular effects, however, are not fully understood. We report a 35-year-old woman who developed recurrent hand erythema …