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Prediction of microRNAs affecting the syncytin-1 (HERV-W) and syncytin-2 (HERV-FRD) genes regulation in endometriosis and miscarriage.

Abnormal expression levels of microRNAs are associated with numerous diseases in the female reproductive tract. A small subset of human endogenous retroviruses (HERVs) genes have retained open reading frames (ORFs) …

Published: Dec. 6, 2025, midnight
Detection of peritoneal, ovarian, and bowel endometriosis using FTIR spectroscopy and machine learning.

This study evaluated the diagnostic potential of Fourier-transform infrared (FTIR) spectroscopy combined with machine learning for the detection of ovarian, bowel, and peritoneal endometriosis. The Boruta algorithm was applied to …

Published: Nov. 23, 2025, midnight
Extracellular Trap-Related Genes as Potential Diagnostic Biomarkers for Endometriosis.

Endometriosis (EM), a prevalent gynecological disorder in reproductive-age women, lacks reliable noninvasive diagnostic tools. EM may be detected by neutrophil extracellular traps (NETs), which are essential to inflammation and immunological …

Published: Nov. 19, 2025, midnight
Machine-learning-derived prediction models of recurrence of ovarian endometriosis after laparoscopic surgery.

Endometriosis is a long-term health problem that affects a significant number of women globally. Among the various forms of endometriosis, ovarian endometriosis (OEM) is the most prevalent. This research aimed …

Published: Nov. 10, 2025, midnight
Identified endoplasmic reticulum stress-related molecular cluster and immune characterization in endometriosis.

Endometriosis is a common disease among women of childbearing age, and endoplasmic reticulum stress (ERS), a response involved in regulating protein homeostasis, has been linked to its pathogenesis. To identify …

Published: Nov. 4, 2025, midnight
Integrated bioinformatics analysis and machine learning identifies FZD4, SRPX2, and COL8A1 as angiogenesis hub genes in endometriosis.

This study aims to identify angiogenesis-associated genes (AAGs) in endometriosis (EM) by integrating bioinformatics analysis with machine learning, and to investigate their underlying mechanisms. Differentially expressed genes (DEGs) were screened …

Published: Oct. 26, 2025, midnight
Pelvic Puzzles: Imaging Non-Traumatic Emergencies of the Female Pelvis: A Comprehensive Review.

Acute non-traumatic pelvic pain represents a frequent and complex diagnostic dilemma in pre-menopausal females presenting to the emergency department due to overlapping symptomatology across pregnancy and non-pregnancy related causes. Radiologists …

Published: Oct. 25, 2025, midnight
Integrative transcriptomic analysis identifies shared EndMT-related gene signatures in endometriosis and recurrent miscarriage.

Endometriosis (EMs) and recurrent miscarriage (RM) represent major reproductive health challenges. This study investigates the involvement of endothelial-mesenchymal transition (EndMT) in these conditions through integrative bioinformatics analysis, focusing on the …

Published: Oct. 21, 2025, midnight
Development and validation of a machine learning-based predictive model for live birth outcomes following fresh embryo transfer in patients with endometriosis.

This study aims to develop a machine learning-based predictive model for patients with endometriosis, with the goal of precisely identifying key factors and reliable predictive markers that influence live birth …

Published: Sept. 23, 2025, midnight
SPP1 as a key modulator of M2 macrophage polarization promotes endometriosis progression via activation of the FAK/PI3K/AKT pathway: A bioinformatics and experimental study.

Endometriosis (EMs) is a gynecological disorder characterized by chronic inflammation and an aberrant immune microenvironment. In this study, we integrated the GSE6364 dataset from the GEO database to identify differentially …

Published: Sept. 17, 2025, midnight
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