Goserelin is a gonadotropin-releasing hormone (GnRH) agonist with a long history of clinical application and well-established efficacy and safety profile. Its mechanism of action centers on sustained GnRH receptor desensitization, …
Ovarian endometriosis (OE) is a chronic, inflammatory gynecological disorder associated with sterility and an elevated risk of ovarian cancer. Despite its high prevalence, the complex molecular mechanisms governing OE pathogenesis …
Fertility preservation refers to the cryopreservation of gametes, embryos, or gonadal tissue before age, disease, or medical treatment affects reproductive capacity. Fertility preservation techniques were originally developed for cancer patients. …
Endometriosis is a chronic estrogen-dependent inflammatory disease affecting approximately 10% of women of reproductive age and characterized by ectopic endometrial-like tissue growth. Although traditionally considered a benign gynecological condition, increasing …
Endometriosis, particularly ovarian endometrioma, is associated with a 2-fold increased risk of ovarian cancer (OC), especially the clear cell and endometrioid subtypes. However, the absolute lifetime risk of OC in …
Advances in kidney transplantation have transformed survival and quality of life for women with end-stage renal disease, necessitating a focus on long-term health care for this population. Female kidney transplant …
Endometriosis is a chronic estrogen-dependent inflammatory disease that shares epidemiological and pathological features with endometrial cancer. However, the cellular and genetic mechanisms underlying this association remain unclear.
Endometriosis is a prevalent gynecologic disorder associated with infertility and increased cancer risk, necessitating the development of sensitive and reliable diagnostic methods. Circulating microRNAs (miRNAs) have emerged as promising noninvasive …
Endometriosis has been associated with several risk factors for cancer, and population-based research has shown that women with endometriosis have a higher risk of several types of cancer. The aim …
Ovarian cancer (OC) remains a major global health issue, often diagnosed late and lacking effective screening.