Single-Cell Transcriptomic Profiling and Machine Learning Integration Unveil Stromal Cell Heterogeneity in Endometriosis.
Endometriosis (EMs) affects approximately 10% of reproductive-age women worldwide, yet its pathogenesis remains incompletely understood. Abnormal cell differentiation and somatic mutations in the ectopic endometrial microenvironment play critical roles in …
Individualized fertility preservation counselling for women with endometriosis-a systematic review.
Endometriosis is a chronic disease that may require surgical intervention under certain circumstances. Although the condition itself is associated with impaired fertility in 30-50% of affected individuals, surgical treatment may …
Macrophage membrane-biomimetic nanovehicles delivering amygdalin halt pyroptosis propagation and alleviate endometriosis-associated neuropathic pain.
The clinical management of endometriosis encounters a significant obstacle: existing therapies inadequately address both the inhibition of ectopic lesion proliferation and the mitigation of the neuroinflammation associated with chronic pain. …
Analyzing the Risk Factors for Recurrence of Endometrioma and Dysmenorrhea in Patients with Endometriosis.
Recurrence of endometrioma and dysmenorrhea after surgery remains a major clinical challenge. Identifying reliable risk factors is essential to optimize individualized treatment and follow-up strategies. However, large-scale data from Chinese …
Polypoid endometriosis mimicking aggressive pelvic malignancy on MRI in a premenopausal woman: A case report.
Polypoid endometriosis is a rare benign variant of endometriosis characterized by exuberant mass-forming endometrial tissue that can closely mimic aggressive pelvic malignancy on imaging. Although it most commonly affects peri- …