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Immune regulatory networks and gut microbiota-associated targets in endometriosis: an integrative multi-omics and network analysis.

Endometriosis is an estrogen-dependent disorder characterized by chronic inflammation, immune dysregulation, and altered hormone metabolism. Although gut microbiota-derived metabolites have been implicated in shaping immune microenvironments and lesion development, the …

Published: Sept. 8, 2026, midnight
Interleukin-10 in endometriosis: a systematic review of systemic and local immune compartment differences.

Endometriosis is a chronic inflammatory disease affecting approximately 10% of reproductive-age women. Immune dysregulation is central to its pathophysiology and interleukin-10 (IL-10) may contribute to immune tolerance, angiogenesis, and fibrosis.

Published: Sept. 8, 2026, midnight
Hippo pathway in endometriosis pathogenesis: from cellular dysregulation to therapeutic opportunities.

Endometriosis is a chronic, heterogeneous gynaecological disorder characterised by the presence of endometrial-like tissue outside the uterine cavity and is associated with pain, infertility, and reduced quality of life. Emerging …

Published: Sept. 8, 2026, midnight
Association Between Endometriosis and Autoimmune Thyroid Disease Using a Multicenter Observational Medical Outcomes Partnership (OMOP) Common Data Model.

Background: Endometriosis affects approximately 6-10% of women of reproductive age-an estimate that varies substantially with the diagnostic standard applied-and is increasingly recognized as a systemic inflammatory disease. Growing evidence implicates …

Published: Sept. 7, 2026, midnight
Immune-nutritional interactions in endometriosis: current evidence and future perspectives in disease management.

Endometriosis is a chronic estrogen-dependent inflammatory disorder affecting approximately 10% of women of reproductive age. It remains a major contributor to chronic pelvic pain, infertility, and reduced quality of life. …

Published: Sept. 7, 2026, midnight
Phytochemicals Modulating Receptor Tyrosine Kinase Signaling Networks in Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory condition that is marked by the growth of lesions outside the uterus, along with angiogenesis, fibrosis, immune dysregulation, and pain sensitization. There is now …

Published: Sept. 7, 2026, midnight
The lactate-myeloid-derived suppressor cells axis in endometriosis from molecular reprogramming to translational therapies: A review article.

Endometriosis is a complex chronic condition, driven by estrogen, characterized by the growth of endometrial-like tissue outside the uterus. This often-debilitating disease affects millions of women globally, manifesting as severe …

Published: Sept. 6, 2026, midnight
Elevated Neutrophil Count as a Causal Risk Factor for Endometriosis: A Mendelian Randomization Study.

Endometriosis is a chronic inflammatory gynecological disorder where immune dysregulation plays a central role in its pathogenesis. While previous observational studies have reported associations between circulating blood cell counts and …

Published: Sept. 5, 2026, midnight
Modulating the Estrobolome and Inflammatory Microenvironment in Endometriosis: The Role of Microbiome-Targeted Interventions and Nutritional Compounds.

Endometriosis is a chronic estrogen-dependent systemic inflammatory disorder characterized by ectopic implantation of endometrial-like tissue, primarily on the ovaries, pelvic peritoneum, and bowel. According to the World Health Organization (WHO) …

Published: Sept. 3, 2026, midnight
2-Deoxyglucose Dendrimer-Enabled Niclosamide Delivery to FRβ-Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia.

Endometriosis (EuE) is a chronic, incurable disease. Due to limited efficacy, high recurrence rates, and serious side effects of current treatments, development of new, targeted, nonhormonal therapies is urgently needed. …

Published: Aug. 30, 2026, midnight
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