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Neuroinflammation is responsible for pain in endometriosis -Targeting the JAK-STAT Pathway and Mast Cell Activation - Frontiers

Neuroinflammation is responsible for pain in endometriosis -Targeting the JAK-STAT Pathway and Mast Cell Activation Frontiers

Published: July 31, 2025, 8:44 p.m.
Unveiling the Mechanisms of Pain in Endometriosis: Comprehensive Analysis of Inflammatory Sensitization and Therapeutic Potential.

Endometriosis is a complicated, estrogen-dependent gynecological condition with a high morbidity rate. Pain, as the most common clinical symptom of endometriosis, severely affects women's physical and mental health and exacerbates …

Published: Feb. 19, 2025, midnight
The Role of Inflammatory Markers NLR and PLR in Predicting Pelvic Pain in Endometriosis.

Background/Objectives: Chronic inflammation plays a critical role in pelvic pain among endometriosis patients. This study examines the association between inflammatory markers-specifically the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR)-and pelvic …

Published: Dec. 30, 2024, midnight
Nociplastic Pain in Endometriosis: A Scoping Review.

Endometriosis is an inflammatory chronic condition associated with nociceptive, neuropathic, and nociplastic pain. Central sensitization (CS) is the primary nociplastic pain mechanism. However, there are currently no standardized methods for …

Published: Dec. 10, 2024, midnight
Soluble adhesion molecules in serum and peritoneal fluid are associated with pelvic pain in endometriosis.

To investigate the association between soluble adhesion molecules (sE-cadherin, sE-selectin, sICAM-1, sVCAM-1) in serum and peritoneal fluid and pelvic pain in infertile women with endometriosis.

Published: Nov. 8, 2024, midnight
Pingchong Jiangni recipe through nerve growth factor/transient receptor potential vanilloid 1 signaling pathway to relieve pain in endometriosis model rats - ScienceDirect.com

Pingchong Jiangni recipe through nerve growth factor/transient receptor potential vanilloid 1 signaling pathway to relieve pain in endometriosis model rats ScienceDirect.com

Published: Jan. 10, 2024, 8 a.m.
Psychological interventions improve quality of life despite persistent pain in endometriosis: results of a 3-armed randomized controlled trial.

Despite standard medical treatment endometriosis is often associated with disabling pain and poor quality of life (QoL). Studies indicate that psychological interventions (PIs) may improve pain and QoL, yet studies …

Published: Feb. 17, 2023, midnight
Endometriosis pain and epithelial neutrophil activating peptide-78 levels.

Endometriosis is a chronic gynecological disorder involved in the pathogenesis of chronic pelvic pain, based on a probable up regulation of the inflammatory system. The objective of the study is …

Published: Feb. 25, 2022, midnight
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