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Interleukin-17A as a key driver for cell migration, proliferation, inflammation, and nerve infiltration in deep endometriosis.

Deep endometriosis (DE) is the most severe subtype of endometriosis, marked by aggressive cellular behavior and debilitating pain. However, the molecular mechanisms underlying DE pathogenesis remain poorly understood. In this …

Published: June 15, 2026, midnight
A transdiagnostic cognitive model of depression and anxiety in chronic inflammatory disease: Evidence from multiple sclerosis and endometriosis.

Depressive and anxiety symptoms are prevalent in Multiple Sclerosis (MS) and Endometriosis (EMS), yet their underlying processes remain poorly understood. Guided by a transdiagnostic framework (Nolen-Hoeksema & Watkins, 2011), this …

Published: June 14, 2026, midnight
RNF34 restrains endometriosis through SREBP1-dependent metabolic-immune crosstalk.

Endometriosis is a chronic inflammatory disease with cancer-like features, yet the mechanisms linking metabolic dysregulation to immune remodeling during lesion progression remain poorly understood. Here, we identify the ubiquitin E3 …

Published: June 13, 2026, midnight
Endometriosis-associated Pain: Mechanism, Neuroimmune Signature, and Translational Precision Strategies.

Endometriosis affects approximately 10% of reproductive-aged women worldwide and is a leading cause of chronic pelvic pain. Despite its high prevalence and substantial socioeconomic burden, the mechanisms underlying endometriosis-associated pain …

Published: June 10, 2026, midnight
Follicular fluid cytokine and homocysteine profiles in poor ovarian responders with and without sonographic endometrioma: A comparative study.

To compare follicular fluid (FF) cytokine and homocysteine profiles in women with poor ovarian response (POR) undergoing in vitro fertilization (IVF), with and without sonographic endometrioma, and to explore potential …

Published: June 6, 2026, midnight
Enhanced detection of vascularization in rectal endometriosis: A comparative study of microvascular flow and power Doppler.

Conventionally, rectal endometriotic nodules have been considered as poorly vascularized. However, new, more sensitive, Doppler techniques have been developed recently for assessing microvascularization. These new techniques might allow microvascularity in …

Published: June 5, 2026, midnight
The needs, preferences, and priorities for supportive healthcare in people living with endometriosis: A qualitative exploratory study.

Although pain, poor quality of life and symptoms of anxiety and depression are common in people with endometriosis, consumer views regarding supportive care needs are limited. Using a descriptive phenomenological …

Published: June 2, 2026, midnight
Endometrial BCL6 Expression and Reproductive Outcomes in Infertile Women: A Systematic Review.

Background/Objectives: Endometrial B-cell lymphoma 6 (BCL6) overexpression has been proposed as a marker of progesterone resistance, occult endometriosis, and endometrial dysfunction in infertile women. Its possible association with reproductive outcomes …

Published: June 2, 2026, midnight
Assessment of Mycotoxin Exposure in Women Undergoing Assisted Reproduction: A Study of Urinary Biomarkers Related to Oocyte and Embryo Development.

Mycotoxins are widespread food contaminants, and urinary biomarkers reflect recent dietary exposure. Although mycotoxins have been implicated in reproductive toxicity, their impact on human oocyte and embryo development remains poorly …

Published: May 26, 2026, midnight
Endometriosis disrupts oocyte metabolism and cortical granule function, impairing fertilization.

Endometriosis is a chronic inflammatory disease strongly associated with reduced oocyte quality and subfertility, yet the underlying cytoplasmic defects remain poorly understood.

Published: May 25, 2026, midnight
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