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Serum response factor is essential for endometrial function and prevention of inflammatory fibrosis.

Pregnancy requires a supportive uterine environment facilitated by steroid hormone-regulated differentiation of endometrial stromal fibroblasts into decidual cells and tight control of inflammation. Serum response factor (SRF) is a widely …

Published: Oct. 28, 2025, midnight
RND3 Inhibits Endometriosis Progression by Regulating Autophagy and Oxidative Stress Through PLEKHG5.

Endometriosis (EMS) is a chronic gynecological disease. RND3 is recognized as a potential autophagy-related biomarker in EMS. The aim of this study was to investigate the regulatory role of RND3 …

Published: Oct. 26, 2025, midnight
Honokiol inhibits cell migration and invasion by blocking EMT via Snail/Slug axis in endometriosis.

Endometriosis, a common gynecological disease, leads to dysmenorrhea and infertility. EMT process was closely related to the pathology of endometriosis. More therapies were required to be explored for endometriosis management. …

Published: Oct. 22, 2025, midnight
Metastatic endometrial stromal sarcoma with sex cord and neuroendocrine differentiation harboring a complex gene fusion - BioMed Central

Metastatic endometrial stromal sarcoma with sex cord and neuroendocrine differentiation harboring a complex gene fusion BioMed Central

Published: Oct. 16, 2025, 2:22 p.m.
PMEPA1-Mediated Treg Cell Impairment Promotes Endometrial Stromal Invasion via Excessive PI3K/AKT Signaling in Endometriosis.

Although immune dysregulation is implicated in the pathogenesis of endometriosis (EMs), the specific role of prostate transmembrane protein androgen induced 1 (PMEPA1) in modulating the function of regulatory T cells …

Published: Oct. 16, 2025, midnight
Multidisciplinary Management of Intracardiac Tumor Thrombus in Low-Grade Endometrial Stromal Sarcoma: Case Report and Literature Review - Frontiers

Multidisciplinary Management of Intracardiac Tumor Thrombus in Low-Grade Endometrial Stromal Sarcoma: Case Report and Literature Review Frontiers

Published: Oct. 15, 2025, 9:11 a.m.
ROBO3 Drives Endometriosis Progression via Dual Wnt/β-Catenin Activation and M2 Macrophage Polarization.

Endometriosis, a prevalent gynecological disorder marked by ectopic growth of endometrial-like tissue, demonstrates malignant tumor-like properties including aggressive adhesion and invasiveness. Emerging evidence implicates roundabout guidance receptor 3 (ROBO3) in …

Published: Oct. 15, 2025, midnight
Identification and Validation of Iron Metabolism-Related Biomarkers in Endometriosis: A Mendelian Randomization and Single-Cell Transcriptomics Study.

Studies have shown that the iron concentration in the peritoneal fluid of women is associated with the severity of endometriosis. Therefore, investigation of iron metabolism-related genes (IM-RGs) in endometriosis holds …

Published: Oct. 9, 2025, midnight
Activated CD8(+) tissue-resident memory T cells impact the endometrial receptivity in minimal/mild endometriosis.

Endometrial immune disorders create an inhospitable endometrial environment for embryonic nidation in endometriosis. CD8 + tissue resident memory T cells (CD8 +TRM) are abundant tissue resident immune cells in endometrium, …

Published: Oct. 8, 2025, midnight
Insufficient NNMT promotes autophagy and disrupts progesterone signaling in endometrial stromal cells in recurrent implantation failure by modulating the H3K9me3-ALDH1A3 pathway - Nature

Insufficient NNMT promotes autophagy and disrupts progesterone signaling in endometrial stromal cells in recurrent implantation failure by modulating the H3K9me3-ALDH1A3 pathway Nature

Published: Oct. 7, 2025, 3:26 p.m.
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