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Metabolomics Analysis Reveals Gut Microbiota-Associated Sakuranin Modulates Endometrial Stem Cell Differentiation and Inflammation to Alleviate Pain in Endometriosis.

Endometriosis (EMS) is characterized by pain symptoms that seriously affect patients' quality of life. Gut microbiome-related metabolites (GMRM) play an important role in the process of EMS. However, the role …

Published: Feb. 17, 2026, midnight
A Previous History of Endometriosis Elevates Irritable Bowel Syndrome Risk in Middle-Aged and Older Women: A UK Biobank Cohort Study of 225,703 Participants.

Endometriosis (EMT) and irritable bowel syndrome (IBS) disproportionately affect middle-aged and older women, where overlapping symptoms (e.g., chronic pelvic pain, bloating) and shared inflammatory mechanisms may drive comorbidity. However, large-scale …

Published: Feb. 16, 2026, midnight
Breaking the silence and building strength; rethinking menopause care through exercise and cultural insight.

Menopause remains a largely neglected aspect of women's health in many low- and middle-income countries (LMICs), particularly across Asia, Africa, and the Middle East. Despite the profound physical, cognitive, and …

Published: Feb. 16, 2026, midnight
Symptom Profiles and Anatomical Distribution of Deep Infiltrating Endometriosis.

Endometriosis is known to affect women worldwide, and most commonly involves chronic pelvic pain and infertility. Deep infiltrating endometriosis (DIE) is a condition that may involve the bladder, ureter, and …

Published: Feb. 16, 2026, midnight
Fertility after endometriosis surgery: a systematic review and meta-analysis comparison of primary versus multiple surgical interventions.

Symptoms of endometriosis are often incompletely managed and recurrent surgeries are commonplace. The impact of re-operation on fertility remains unclear. This systematic review compares fertility outcomes in patients who underwent …

Published: Feb. 15, 2026, midnight
Efficacy and tolerability of elagolix in adolescents and young adults with endometriosis: a small, single-center retrospective cohort study.

To evaluate the efficacy and tolerability of the gonadotropin-releasing hormone antagonist elagolix for endometriosis-associated pain symptoms in adolescents and young adults (AYA).

Published: Feb. 14, 2026, midnight
Association of body mass index on sexual function in women with endometriosis: A cross-sectional study.

This study aimed to investigate the association between body mass index (BMI) and sexual function, measured by the Female Sexual Function Index (FSFI), in women with endometriosis, adjusting for the …

Published: Feb. 13, 2026, midnight
Misdiagnosis rate of endometriosis and strategies employed to identify endometriosis by analyzing patient characteristics in low-resource settings.

Endometriosis is a major gynecologic health issue affecting ~10% of women and girls of reproductive age worldwide. Despite its high prevalence, no curative treatment exists. Early diagnosis and treatment are …

Published: Feb. 13, 2026, midnight
Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach.

Endometriosis is a complex, estrogen-dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, …

Published: Feb. 13, 2026, midnight
Impact of lesion size and localization on symptom severity in intestinal endometriosis.

Intestinal endometriosis (IE) often presents with dyschezia, gastrointestinal (GI) dysfunction, dyspareunia, and dysmenorrhea. The impact of lesion localization and size on the severity of symptoms remains insufficiently studied, complicating preoperative …

Published: Feb. 12, 2026, midnight
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