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PRT-064040: A nasal spray of novel, potent, and selective calcitonin gene-related peptide receptor antagonist for migraine.

Calcitonin gene-related peptide (CGRP), a neuropeptide, has been implicated in autoimmune diseases, endometriosis, tumors, and primary headaches, including migraine. The development of a novel, fast-acting CGRP receptor antagonist administered via …

Published: June 17, 2026, midnight
The role of IL-33/ST2 signaling in female reproductive diseases.

Female reproductive tissues repeatedly undergo controlled inflammation, immune adaptation, and tissue repair. Interleukin-33 (IL-33) and its receptor suppression of tumorigenicity 2 (ST2) sit at the center of these processes, but …

Published: June 12, 2026, midnight
Deep infiltrating endometriosis presenting as acute abdomen with extremely elevated tumor markers: a cancer-mimicking case.

Deep infiltrating endometriosis (DIE) is a rare and severe subtype of endometriosis that can cause marked distortion of pelvic anatomy. Diagnosis becomes particularly challenging when it presents as an acute …

Published: June 11, 2026, midnight
Mullerian Adenosarcomas with Extrauterine Involvement, Sarcomatous Overgrowth and MDM2 Amplification: A Diagnostic Challenge.

Extrauterine presentation of Mullerian adenosarcoma is rare and thought to either arise from endometriosis or from spread from a primary uterine or ovarian origin. When accompanied by sarcomatous overgrowth, particularly …

Published: June 10, 2026, midnight
Squamous Cell Carcinoma Arising From Mature Cystic Teratoma in a 39-Year-Old Woman: A Case Report.

Ovarian carcinomas represent the second most common malignancy of the female genital tract; however, primary squamous cell carcinoma (SCC) is a rare subtype. Most of these tumors arise from malignant …

Published: June 10, 2026, midnight
Endometriotic cyst mimicking recurrence after treatment for ovarian immature teratoma: a case report.

Endometriosis is common in reproductive-age women, but the development of an endometriotic cyst that mimics tumor recurrence during follow-up after treatment for ovarian immature teratoma poses a significant diagnostic challenge, …

Published: June 9, 2026, midnight
FDG PET/CT in a Case of Clear Cell Carcinoma Arising From Abdominal Wall Endometriosis.

Abdominal wall endometriosis is rare. Malignant transformation of abdominal wall endometriosis is extremely rare. We describe FDG PET/CT findings in a case of clear cell carcinoma arising from abdominal wall …

Published: June 8, 2026, midnight
High-concentration estradiol promotes platelet activation and thrombosis through Src-ADP axis.

Pregnant women, as well as patients with endometriosis and some ovarian tumors, may experience a state of high estrogen levels. However, the role of high estrogen in platelet function and …

Published: June 3, 2026, midnight
An AI model decodes tumor mutations to predict treatment response - Drug Discovery News

An AI model decodes tumor mutations to predict treatment response Drug Discovery News

Published: June 1, 2026, 7:29 p.m.
Investigation of the effect of TNF-α levels on infertility duration and infertility characteristics in endometriosis patients presenting with infertility complaints.

Endometriosis is a chronic inflammatory disorder frequently associated with infertility. Tumor necrosis factor-alpha (TNF-α) is involved in inflammatory pathways; however, the clinical relevance of serum TNF-α in relation to infertility …

Published: June 1, 2026, midnight
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