Ovarian endometriosis is a chronic inflammatory disease characterized by extensive tissue remodeling and fibrosis, which significantly impacts female reproductive health. This study demonstrates that ectopic endometrium (Ect) in patients with …
Daughters of women with endometriosis are known to be at increased risk of developing this disease. Using a mouse model, we demonstrate uterine dysfunction reminiscent of endometriosis patients can also …
Women with endometriosis experience chronic cyclic pelvic pain (CCPP) or chronic persistent pelvic pain (CPPP), both of which may be incapacitating even after treatment. Emotional dysregulation in endometriosis impedes patient …
Endometriosis is a systemic inflammatory disease in which immune dysregulation and oxidative stress contribute to pain and impaired quality of life. This study aimed to examine whether antioxidant and inflammatory …
Background: Endometriosis affects 10% of reproductive-aged women globally and is one of the major causes of infertility. It is a debilitating, chronic condition with an average diagnostic delay of up …
Endometriosis is a chronic inflammatory and estrogen-dependent disease in which pain remains the leading cause of impaired quality of life. Hormonal therapies constitute the cornerstone of medical management and include …
To assess whether specific markers of oxidative stress and DNA damage are expressed at higher levels in primordial follicles of patients with endometriomas compared to age-matched controls.
Endometriosis (EMs) is a chronic gynecological disease with poorly understood pathogenesis. This study integrated lipidomics and transcriptomics to systematically investigate aberrant sphingolipid metabolism in EMs, aiming to identify pathogenic mechanisms …
Female reproductive health is increasingly affected by conditions such as infertility, polycystic ovary syndrome (PCOS), and endometriosis. Given the impact of modifiable lifestyle factors, nutrition has emerged as a potential …
Endometriosis (EM) is a chronic inflammatory gynaecological disorder affecting approximately 10% of women of reproductive age. Early diagnosis remains challenging because definitive diagnosis still relies on invasive surgical confirmation. This …