Latest Articles

Publication Date
The Gut-Endometriosis Axis: Genetic Mechanisms and Public Health Implications.

Background/Objectives: Endometriosis is a chronic, estrogen-driven gynecological disorder affecting approximately 10% of reproductive-aged women worldwide, with significant physical, psychosocial, and socioeconomic impacts. Recent research suggests a possible involvement of the …

Published: July 30, 2025, midnight
Relugolix in Monotherapy and Combined Therapy for the Treatment of Uterine Diseases and Its Effects on Bones: A Systematic Review.

Background: Uterine fibroids (UFs) and endometriosis are gynecological conditions that significantly increase morbidity among women of reproductive age. Relugolix, a novel gonadotropin-releasing hormone receptor antagonist, is approved in combined therapy …

Published: July 30, 2025, midnight
Leveraging epigenetic aberrations in the pathogenesis of endometriosis: from DNA methylation to non-coding RNAs.

Endometriosis is highly underdiagnosed and undertreated gynecological disorder, with diagnosis often delayed by 8-12 years. This delay can have serious consequences including infertility. Currently, the gold standard for endometriosis diagnosis …

Published: July 28, 2025, midnight
The Prognosis of Endometriosis Correlates With Elevated Expression of LncRNA-ANRIL.

Background: Endometriosis is a chronic condition that affects the endometrium, the lining of the uterus. The endometrium typically thickens and discharges during the menstrual cycle, resulting in menstruation. Endometriosis is …

Published: July 26, 2025, midnight
Endometriosis-Associated Periodontal Disease: A Large Cohort Perspective Study.

Endometriosis is a chronic estrogen-dependent gynecological disease affecting millions of women worldwide. Besides its well-established impact on reproductive health, emerging evidence suggests a potential association between endometriosis and periodontal disease. …

Published: July 26, 2025, midnight
Association Between Dysmenorrhea and Endometrial Cancer: A Mendelian Randomization Study.

Background: Dysmenorrhea is a common gynecological symptom among reproductive-aged women, associated with substantial pain and decreased quality of life. Previous studies have suggested that inflammatory and hormonal fluctuations linked to …

Published: July 23, 2025, midnight
Menopause as a Critical Turning Point in Lipedema: The Estrogen Receptor Imbalance, Intracrine Estrogen, and Adipose Tissue Dysfunction Model.

Lipedema is a chronic, estrogen-sensitive adipose tissue disorder characterized by disproportionate subcutaneous fat accumulation, fibrosis, inflammation, and resistance to fat mobilization. Despite its high prevalence, lipedema remains poorly understood and …

Published: July 23, 2025, midnight
Factors contributing to the delayed diagnosis of endometriosis-a systematic review and meta-analysis.

Endometriosis is a prevalent gynecological disorder that is estimated to affect approximately 10% of women of childbearing age globally. However, the condition remains significantly under-or misrecognized, and the mean time …

Published: July 22, 2025, midnight
Increase in Angiogenesis and Vascularization in Patient-Derived Endometriosis Tissue: Insights from a 3D In Vivo Model.

Endometriosis is a gynecological disorder characterized by endometrial-like tissue outside the uterus. This study evaluates the vascularization and proliferation of human endometriosis and endometrium tissues engrafted onto the chorioallantoic membrane …

Published: July 22, 2025, midnight
Diagnostic Potential of Serum Circulating miRNAs for Endometriosis in Patients with Chronic Pelvic Pain.

Background: Endometriosis is a chronic gynecological condition marked by ectopic endometrial-like tissue, leading to inflammation, pain, and infertility. Diagnosis is often delayed by up to 10 years. Identifying non-invasive biomarkers …

Published: July 21, 2025, midnight
Link copied to clipboard!
Subscribe to Our Newsletter

Stay updated with our latest articles!