Descriptive overview of gene variants potentially affecting female infertility treatments: A systematic review.
Pharmacogenetics is an emerging discipline that explores how genetic variants affect drug response, potentially leading to side effects or treatment failure. Although widely applied in other medical specialties, its use …
Microbiota and infertility: a translational review of mechanisms and clinical applications in assisted reproduction.
Infertility constitutes a major global health concern, affecting approximately 17.5% of couples of reproductive age. Although advances in assisted reproductive technologies (ART) have expanded treatment options, success rates remain highly …
Botulinum toxin for endometriosis-associated chronic pelvic pain: a randomised, double-masked, parallel, phase 2 trial.
Chronic pelvic pain affects one in four women. Botulinum toxin, approved for chronic migraine and cervical dystonia pain, is an emerging treatment for other pain conditions. We evaluated intramuscular pelvic …
Paeonia × suffruticosa Andrews leaves improve endometriosis with anxiety/depression by regulating microglial polarization via JAK2/STAT3 pathway.
Endometriosis (EMs) is a chronic inflammatory disease often treated with blood-activating and stasis-resolving therapies. Anxiety and depression are common mental comorbidities in patients with EMs. There are no medications available …
Endometriosis and Reproductive Sparing Surgery: A Narrative Review and AGREE II-S-Based Evaluation of International Guidelines.
Endometriosis is a complex disease that may affect a woman's fertility and quality of life. Owing to substantial variations in symptom severity, lesion distribution, and reproductive impact, its management presents …